Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 12/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7709836 | 0.72 | SMN1; SMN2 (0.47) | SMN1; SMN2HTR1AADRA1BADRA1ADRD2 | |
| SCHEMBL14820495 | 0.70 | SMN1; SMN2 (0.46) | SMN1; SMN2HTR1AADRA1BADRA1ADRD2 | |
| SCHEMBL9271889 | 0.67 | SMN1; SMN2 (0.43) | SMN1; SMN2HTR1AADRA1BADRA1ADRD2 | |
| SCHEMBL7301175 | 0.67 | SMN1; SMN2 (0.43) | SMN1; SMN2HTR1AADRA1BADRA1ADRD2 | |
| SCHEMBL10299522 | 0.67 | SMN1; SMN2 (0.43) | SMN1; SMN2HTR1AADRA1BADRA1ADRD2 | |
| SCHEMBL12308312 | 0.67 | SMN1; SMN2 (0.43) | SMN1; SMN2HTR1AADRA1BADRA1ADRD2 | |
| SCHEMBL11930032 | 0.67 | SMN1; SMN2 (0.43) | SMN1; SMN2HTR1AADRA1BADRA1ADRD2 | |
| SCHEMBL12601433 | 0.67 | CHRM2 (0.46) | SMN1; SMN2HTR1AADRA1BADRA1ADRD2 | |
| SCHEMBL3379242 | 0.66 | SMN1; SMN2 (0.46) | SMN1; SMN2HTR1AADRA1BADRA1ADRD2 | |
| SCHEMBL7835878 | 0.66 | SMN1; SMN2 (0.42) | SMN1; SMN2HTR1AADRA1BADRA1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623616-A1 | Heterocyclic compounds and process for the preparation thereof | EGIS GYOGYSZERGYAR RT. (HU) | 1994-11-09 | — | — | EP | claimed |
| EP-0623616-A1 | Heterocyclic compounds and process for the preparation thereof | EGIS GYOGYSZERGYAR RT. (HU) | 1994-11-09 | — | — | EP | disclosed |