Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL11376826 | 0.97 | — | — | |
| Alcohol SCHEMBL377733 | 0.97 | ALDH1A1 (0.43) | ALDH1A1TSHREPHX1PRMT3CARM1 | |
| Alcohol SCHEMBL8410950 | 0.93 | ALDH1A1 (0.40) | ALDH1A1TSHREPHX1PRMT3CARM1 | |
| Alcohol SCHEMBL7255710 | 0.93 | ALDH1A1 (0.40) | ALDH1A1TSHREPHX1PRMT3CARM1 | |
| Water SCHEMBL5930817 | 0.93 | — | — | |
| Water SCHEMBL2274840 | 0.93 | PRMT3 (0.35) | EPHX1PRMT3CARM1PRMT6PRMT1 | |
| Water SCHEMBL28209888 | 0.93 | — | — | |
| Water SCHEMBL2274846 | 0.93 | PRMT3 (0.35) | EPHX1PRMT3CARM1PRMT6PRMT1 | |
| Water SCHEMBL5496497 | 0.90 | PRMT3 (0.33) | EPHX1PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL6247615 | 0.89 | CARM1 (0.37) | ALDH1A1TSHREPHX1PRMT3CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583970-A1 | Hydroisomerization process using catalysts based on noble metal ECR-1 or mazmorite zeolites | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1994-02-23 | — | — | EP | disclosed |
| US-4159964-A | Metal chelate catalyst and alkanolamine hydroxide on adsorptive support | UOP INC. (US) | 1979-07-03 | — | — | US | disclosed |
| US-4127474-A | Treating a petroleum distillate with an alkanolamine hydroxide and a supported oxidation catalyst impregnated with polynuclear aromatic sulfonic acid | UOP INC. (US) | 1978-11-28 | — | — | US | disclosed |
| US-4124494-A | Treating a petroleum distillate with a supported metal phthalocyanine and an alkanolamine hydroxide | UOP INC. (US) | 1978-11-07 | — | — | US | disclosed |