Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 5/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10878260 | 0.85 | MEN1 (0.43) | MEN1KMT2ANUDT1NOS3NOS2 | |
| SCHEMBL3625881 | 0.80 | HSP90AB1 (0.46) | MEN1KMT2AHSP90AB1NOS3NOS2 | |
| SCHEMBL12781970 | 0.80 | MEN1 (0.41) | MEN1KMT2ANUDT1HSP90AB1NOS3 | |
| SCHEMBL11305748 | 0.79 | ADORA3 (0.38) | MEN1KMT2AHSP90AB1NOS3NOS2 | |
| SCHEMBL3461180 | 0.78 | KMT2A (0.59) | MEN1KMT2ANOS3NOS2KDM4E | |
| SCHEMBL3461179 | 0.78 | MEN1 (0.39) | MEN1KMT2ANUDT1NOS3NOS2 | |
| SCHEMBL4249530 | 0.77 | ADORA3 (0.56) | MEN1KMT2AL3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL2614898 | 0.76 | KMT2A (0.57) | MEN1KMT2ANOS3NOS2KDM4E | |
| SCHEMBL3735503 | 0.74 | NUDT1 (0.59) | MEN1KMT2ANUDT1MAPT | |
| SCHEMBL8018804 | 0.72 | KMT2A (0.49) | MEN1KMT2AHSP90AB1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582261-A1 | Cephalosporin compounds and processes for the preparation thereof | LUCKY LTD. (KR) | 1994-02-09 | — | — | EP | disclosed |
| US-4565864-A | INTERMEDIATES FOR BRONCHODILATORS | RIKER LABORATORIES, INC. (US) | 1986-01-21 | — | — | US | disclosed |
| US-4503050-A | BRONCHODILATORS | RIKER LABORATORIES, INC. (US) | 1985-03-05 | — | — | US | disclosed |