Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12781970 | 0.89 | MEN1 (0.41) | MEN1KMT2ANOS3NOS2LMNA | |
| SCHEMBL3461179 | 0.87 | MEN1 (0.39) | MEN1KMT2ANOS3NOS2LMNA | |
| SCHEMBL3461180 | 0.87 | KMT2A (0.59) | MEN1KMT2ANOS3NOS2LMNA | |
| SCHEMBL9413801 | 0.85 | MEN1 (0.41) | MEN1KMT2ANOS3NOS2LMNA | |
| SCHEMBL2614898 | 0.85 | KMT2A (0.57) | MEN1KMT2ANOS3NOS2LMNA | |
| SCHEMBL16302718 | 0.83 | ADORA3 (0.57) | MEN1KMT2AKDM4ENUDT1CYP1A2 | |
| SCHEMBL12859522 | 0.78 | NUDT1 (0.64) | KMT2ALMNAKDM4ESMN1; SMN2HTT | |
| SCHEMBL5914036 | 0.73 | MEN1 (0.51) | MEN1KMT2ALMNAKDM4EGAA | |
| SCHEMBL11445700 | 0.70 | MAPT (0.50) | NOS3NOS2KDM4ENPSR1NUDT1 | |
| SCHEMBL17812892 | 0.70 | NOS3 (0.54) | NOS3NOS2GAASMN1; SMN2NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065811-B1 | DISPERSE AZOPYRIMIDINE DYESTUFFS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-01-02 | — | — | EP | disclosed |
| EP-0065811-A1 | Disperse azopyrimidine dyestuffs | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-01 | — | — | EP | disclosed |