Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | FABP3 | P05413 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28442446 | 0.83 | MRGPRX4 (0.57) | MRGPRX4MAPTNR4A2NR4A1NR4A3 | |
| SCHEMBL5318479 | 0.80 | MAPT (0.57) | MRGPRX4MAPTNR4A2NR4A1NR4A3 | |
| SCHEMBL6666901 | 0.79 | L3MBTL1 (0.74) | MRGPRX4MAPTNR4A2NR4A1NR4A3 | |
| SCHEMBL9650487 | 0.78 | L3MBTL1 (0.55) | MAPTNR4A2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4888735 | 0.78 | NR4A2 (0.56) | MRGPRX4NR4A2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL658196 | 0.77 | PDPK1 (0.68) | MRGPRX4MAPTNR4A2NR4A1NR4A3 | |
| SCHEMBL29579676 | 0.77 | PDPK1 (0.68) | MRGPRX4MAPTNR4A2NR4A1NR4A3 | |
| SCHEMBL22480856 | 0.76 | MRGPRX4 (1.00) | MRGPRX4NR4A2NR4A1NR4A3MEN1 | |
| SCHEMBL9787090 | 0.76 | TDP1 (0.69) | MRGPRX4MAPTL3MBTL1LMNAHPGD | |
| SCHEMBL31531952 | 0.76 | TDP1 (0.69) | MRGPRX4MAPTL3MBTL1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600315-A1 | Use of bentylimidazolyl derivatives as microbiocides for protecting materials | BAYER AG (DE) | 1994-06-08 | — | — | EP | disclosed |
| EP-0255243-B1 | AZOLE DERIVATIVES USEFUL FOR CONTROLLING PLANT DISEASES | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-05-29 | — | — | EP | disclosed |
| US-4780471-A | IMIDAZOLE OR TRIAZOLE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1988-10-25 | — | — | US | disclosed |
| EP-0255243-A1 | Azole derivatives useful for controlling plant diseases | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1988-02-03 | — | — | EP | disclosed |