SCHEMBL6666901

SCHEMBL6666901

O=C(OCc1ccc(Cl)cc1Cl)c1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.74
KMT2A Q03164 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
MEN1 O00255 1/20 0.59
CYP1A2 P05177 1/20 0.59
CYP2D6 P10635 1/20 0.59
CYP2C9 P11712 1/20 0.59
PKM P14618 1/20 0.59
CYP2C19 P33261 1/20 0.59
NR4A2 P43354 2/20 0.58
NR4A1 P22736 1/20 0.58
NR4A3 Q92570 1/20 0.58
MRGPRX4 Q96LA9 1/20 0.57
MAPT P10636 2/20 0.56
SLC6A2 P23975 1/20 0.53
SLC6A3 Q01959 1/20 0.53
PPARG P37231 1/20 0.51
PDPK1 O15530 1/20 0.51
GAA P10253 1/20 0.51
HDAC8 Q9BY41 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2291589 0.88 L3MBTL1 (0.57) L3MBTL1KMT2ATDP1MEN1CYP1A2
SCHEMBL8581278 0.84 L3MBTL1 (0.61) L3MBTL1KMT2ATDP1MEN1CYP1A2
SCHEMBL5421974 0.83 L3MBTL1 (0.72) L3MBTL1KMT2ATDP1NR4A2MAPT
SCHEMBL27997536 0.83 L3MBTL1 (0.71) L3MBTL1KMT2ATDP1MEN1CYP1A2
SCHEMBL9750049 0.82 L3MBTL1 (0.66) L3MBTL1KMT2ATDP1MEN1CYP1A2
SCHEMBL6645333 0.81 MRGPRX4 (0.57) L3MBTL1KMT2ATDP1MEN1CYP1A2
SCHEMBL9414534 0.79 MRGPRX4 (0.61) L3MBTL1KMT2AMEN1CYP1A2CYP2D6
SCHEMBL3292219 0.78 L3MBTL1 (0.60) L3MBTL1KMT2ATDP1MEN1CYP1A2
SCHEMBL5085480 0.77 PPARG (0.71) L3MBTL1KMT2ATDP1PKMMAPT
SCHEMBL2357688 0.77 KMT2A (0.76) L3MBTL1KMT2ATDP1MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1004621-B1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN CHEMICALS LTD (JP) 2004-09-15 EP disclosed
US-6485657-B1 Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer TEIJIN, LIMITED (JP) 2002-11-26 US disclosed
EP-1004621-A1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN LIMITED (JP) 2000-05-31 EP disclosed