Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9650496 | 0.93 | MAPT (0.62) | L3MBTL1MAPTKMT2AMEN1HPGD | |
| SCHEMBL657234 | 0.88 | TDP1 (0.55) | L3MBTL1MAPTKMT2AMEN1HPGD | |
| Chloroform SCHEMBL28141196 | 0.85 | NPC1 (0.49) | L3MBTL1MAPTKMT2AMEN1HPGD | |
| SCHEMBL4888739 | 0.83 | GRM5 (0.54) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL4888735 | 0.83 | NR4A2 (0.56) | KMT2AMEN1NPC1RAB9ACYP1A2 | |
| SCHEMBL4689393 | 0.81 | RAB9A (0.56) | L3MBTL1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL1759771 | 0.80 | NR4A2 (0.50) | L3MBTL1NPC1RAB9AALDH1A1CYP1A2 | |
| SCHEMBL10901370 | 0.80 | L3MBTL1 (0.59) | L3MBTL1MAPTKMT2AMEN1HPGD | |
| SCHEMBL9414534 | 0.78 | MRGPRX4 (0.61) | L3MBTL1MAPTKMT2AMEN1HPGD | |
| SCHEMBL8759518 | 0.78 | ALOX5 (0.59) | MAPTKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120783-A | Hydrotalcite, zinc compound, magnesium hydroxide and beta-diketone compound and/or phosphite compound; discoloration inhibition, radiation transparent and heat resistance | KYOWA CHEMICAL INDUSTRY CO., LTD. (JP) | 1992-06-09 | — | — | US | disclosed |
| US-4265903-A | HYPOTENSIVE, ADRENOLYTIC | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1981-05-05 | — | — | US | disclosed |