Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9414543 | 0.90 | KEAP1 (0.32) | KEAP1NFE2L2 | |
| SCHEMBL9414604 | 0.82 | — | — | |
| SCHEMBL9414553 | 0.80 | KEAP1 (0.31) | KEAP1NFE2L2LMNA | |
| SCHEMBL9414552 | 0.78 | KEAP1 (0.32) | KEAP1NFE2L2 | |
| SCHEMBL9414551 | 0.74 | KEAP1 (0.34) | KEAP1NFE2L2 | |
| SCHEMBL9139159 | 0.70 | ALDH1A1 (0.33) | LMNA | |
| SCHEMBL18697361 | 0.66 | CA1 (0.35) | — | |
| SCHEMBL9136759 | 0.65 | KEAP1 (0.31) | KEAP1NFE2L2LMNA | |
| SCHEMBL18697328 | 0.62 | KMT2A (0.48) | — | |
| SCHEMBL9181490 | 0.61 | ALDH1A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603595-A1 | Fibre reactive dyes, method for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-29 | — | — | EP | disclosed |