SCHEMBL9414653

SCHEMBL9414653

Cc1c(C)c(C(N)=O)c(C)c(C(=O)N(C)C)c1C

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.35
ALDH1A1 P00352 2/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.32
EGFR P00533 1/20 0.31
SRC P12931 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8746547 0.89 L3MBTL1 (0.40) L3MBTL1ALDH1A1GAAKMT2AMEN1
SCHEMBL7406703 0.83 POLB (0.50) POLBALDH1A1GAAKMT2AMEN1
SCHEMBL1003996 0.81 POLB (0.52) POLBALDH1A1GAAKMT2AMEN1
SCHEMBL1004648 0.78 POLB (0.55) POLBALDH1A1GAAKMT2AMEN1
SCHEMBL16781055 0.78 POLB (0.55) POLBALDH1A1GAAKMT2AMEN1
Hydrochloric Acid SCHEMBL29030889 0.75 POLB (0.52) POLBALDH1A1GAAKMT2AMEN1
SCHEMBL2221293 0.75 POLB (0.52) POLBALDH1A1GAAKMT2AMEN1
SCHEMBL9414651 0.75 BRD4 (0.34) L3MBTL1KMT2AHTT
SCHEMBL28919248 0.71 POLB (0.39) POLBALDH1A1GAAKMT2AMEN1
SCHEMBL10149876 0.70 POLB (0.42) POLBALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0580546-A2 High temperature self-locking threaded fasteners and method of manufacture NYLOK FASTENER CORPORATION (US) 1994-01-26 EP claimed
EP-0282730-A1 Glass fibre-reinforced polyamide moulding compositions with an increased salt and weather resistance BAYER AG (DE) 1988-09-21 EP disclosed