Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9414653 | 0.89 | POLB (0.38) | L3MBTL1KMT2AHTTEGFRSRC | |
| SCHEMBL9414651 | 0.85 | BRD4 (0.34) | L3MBTL1KMT2AHTT | |
| SCHEMBL15711672 | 0.79 | L3MBTL1 (0.42) | L3MBTL1KMT2AHTTALDH1A1GAA | |
| SCHEMBL13801042 | 0.77 | L3MBTL1 (0.32) | L3MBTL1 | |
| SCHEMBL31294883 | 0.71 | BRD4 (0.32) | L3MBTL1 | |
| SCHEMBL8746549 | 0.71 | KMT2A (0.37) | L3MBTL1KMT2AHTTALDH1A1GAA | |
| SCHEMBL1234975 | 0.67 | LDHA (0.43) | ALDH1A1SMN1; SMN2GFERTSHRCYP1A2 | |
| SCHEMBL1004853 | 0.67 | HPGD (0.46) | L3MBTL1KMT2AHTTALDH1A1GAA | |
| SCHEMBL4047990 | 0.67 | CYP19A1 (0.43) | L3MBTL1KMT2AEGFRSRCALDH1A1 | |
| SCHEMBL15218734 | 0.67 | HDAC6 (0.40) | L3MBTL1KMT2AHTTEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759511-A1 | Improved self-locking fastener, apparatus and method | NYLOK FASTENER CORPORATION (US) | 1997-02-26 | — | — | EP | claimed |
| US-5356254-A | High temperature self-locking threaded fastener | NYLOK FASTENER CORPORATION (US) | 1994-10-18 | — | — | US | claimed |
| EP-0580546-A2 | High temperature self-locking threaded fasteners and method of manufacture | NYLOK FASTENER CORPORATION (US) | 1994-01-26 | — | — | EP | claimed |
| EP-0580546-B1 | High temperature self-locking threaded fasteners and method of manufacture | NYLOK FASTENER CORP (US) | 1997-03-26 | — | — | EP | disclosed |
| US-5356254-A | High temperature self-locking threaded fastener | NYLOK FASTENER CORPORATION (US) | 1994-10-18 | — | — | US | disclosed |
| EP-0580546-A2 | High temperature self-locking threaded fasteners and method of manufacture | NYLOK FASTENER CORPORATION (US) | 1994-01-26 | — | — | EP | disclosed |