Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10822596 | 0.78 | GAA (0.55) | DNMT1RAD52UHRF1HSD17B10ALDH1A1 | |
| SCHEMBL10822501 | 0.74 | DNMT1 (0.49) | DNMT1RAD52UHRF1KDM4EALDH1A1 | |
| SCHEMBL10822386 | 0.73 | MEN1 (0.50) | DNMT1RAD52UHRF1HSD17B10ALDH1A1 | |
| SCHEMBL10822612 | 0.71 | DNMT1 (0.46) | DNMT1RAD52UHRF1HTR1ADRD3 | |
| SCHEMBL8479084 | 0.70 | DNMT1 (0.57) | DNMT1RAD52UHRF1 | |
| SCHEMBL7329166 | 0.70 | DNMT1 (0.57) | DNMT1RAD52UHRF1CA1CA2 | |
| SCHEMBL11833756 | 0.66 | HTR7 (0.65) | PTGS2HTR1AKDM4EALDH1A1HTR7 | |
| SCHEMBL10822551 | 0.66 | GAA (0.46) | DNMT1RAD52UHRF1ALDH1A1ALDH3A1 | |
| SCHEMBL10625887 | 0.65 | PTGS2 (0.55) | PTGS2HTR1ADRD3DRD4HTR7 | |
| SCHEMBL10822558 | 0.64 | PTAFR (0.51) | DNMT1RAD52UHRF1PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594877-A1 | Imidazo(1,2-c)quinazoline derivates as antihyper tensives and anti dysurics | NATIONAL SCIENCE COUNCIL (TW) | 1994-05-04 | — | — | EP | claimed |