Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31563899 | 1.00 | DRD2 (0.43) | DRD2DRD3OPRK1MAPTNFKB1 | |
| SCHEMBL31564089 | 1.00 | DRD2 (0.43) | DRD2DRD3OPRK1MAPTNFKB1 | |
| Hydrochloric Acid SCHEMBL31564255 | 0.76 | PNMT (0.43) | DRD2DRD3OPRK1MAPTNFKB1 | |
| SCHEMBL31564341 | 0.74 | MAPT (0.40) | DRD2DRD3OPRK1MAPTNFKB1 | |
| SCHEMBL20858651 | 0.74 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL31563807 | 0.74 | DRD2 (0.38) | DRD2DRD3ALDH1A1 | |
| SCHEMBL31564100 | 0.74 | DRD2 (0.38) | DRD2DRD3ALDH1A1 | |
| SCHEMBL31563923 | 0.74 | DRD2 (0.38) | DRD2DRD3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL31563867 | 0.73 | DRD2 (0.46) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL31564138 | 0.73 | DRD2 (0.37) | DRD2DRD3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025097104-A1 | THIENYL COMPOUNDS FOR THE TREATMENT OF A CENTRAL NERVOUS SYSTEM DISEASE OR DISORDER | PGI DRUG DISCOVERY LLC (US) | 2025-05-08 | — | — | WO | claimed |
| WO-2025097104-A1 | THIENYL COMPOUNDS FOR THE TREATMENT OF A CENTRAL NERVOUS SYSTEM DISEASE OR DISORDER | PGI DRUG DISCOVERY LLC (US) | 2025-05-08 | — | — | WO | disclosed |
| EP-0579059-A1 | Pyridazinone derivatives and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1994-01-19 | — | — | EP | disclosed |