Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 8/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.33 |
| ▸ | PDE4A | P27815 | 3/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9414692 | 0.90 | SMN1; SMN2 (0.36) | SMN1; SMN2PDE3APDE3BALDH1A1KDM4E | |
| SCHEMBL9414809 | 0.76 | PDE4B (0.35) | SMN1; SMN2PDE3APDE3BALDH1A1KDM4E | |
| SCHEMBL9414927 | 0.74 | PNMT (0.40) | SMN1; SMN2PKM | |
| SCHEMBL9414700 | 0.73 | PDE3B (0.50) | SMN1; SMN2PDE3APDE3BPDE4BPDE4A | |
| SCHEMBL8305010 | 0.73 | HDAC8 (0.43) | MAPTLMNANPY1RNPY2R | |
| Iodide SCHEMBL8309296 | 0.72 | PDE3B (0.49) | SMN1; SMN2PDE3APDE3BPDE4BPDE4A | |
| SCHEMBL9414693 | 0.72 | SMN1; SMN2 (0.36) | SMN1; SMN2PDE3APDE3BKMT2APDE4B | |
| SCHEMBL9383997 | 0.71 | NR1H2 (0.35) | SMN1; SMN2PDE3APDE3BALDH1A1KDM4E | |
| Iodide SCHEMBL8720179 | 0.71 | SMN1; SMN2 (0.35) | SMN1; SMN2PDE3APDE3BKMT2APDE4B | |
| SCHEMBL9414771 | 0.71 | MAPT (0.40) | SMN1; SMN2PDE3APDE3BALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579059-A1 | Pyridazinone derivatives and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1994-01-19 | — | — | EP | disclosed |