SCHEMBL941591

SCHEMBL941591

CC1=CC(C)(C)Nc2cc(C)ccc21

nearest known ligand 0.73

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.73
KDM4E B2RXH2 6/20 0.73
MAPT P10636 4/20 0.73
HPGD P15428 4/20 0.73
HSD17B10 Q99714 3/20 0.73
MEN1 O00255 3/20 0.63
KMT2A Q03164 3/20 0.63
TDP1 Q9NUW8 2/20 0.61
LMNA P02545 1/20 0.61
CYP3A4 P08684 1/20 0.61
L3MBTL1 Q9Y468 2/20 0.59
MAPK1 P28482 1/20 0.53
GAA P10253 1/20 0.51
PGR P06401 13/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31489985 1.00 ALDH1A1 (0.73) ALDH1A1KDM4EMAPTHPGDHSD17B10
Hydrochloric Acid SCHEMBL2174058 0.98 ALDH1A1 (0.71) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL941508 0.85 ALDH1A1 (1.00) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL30973139 0.83 KDM4E (0.83) ALDH1A1KDM4EMAPTHPGDHSD17B10
Hydrochloric Acid SCHEMBL11447400 0.83 ALDH1A1 (0.96) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL21861904 0.81 ALDH1A1 (0.59) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL29802168 0.81 PGR (0.67) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL10894057 0.81 PGR (0.67) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL6649160 0.81 ALDH1A1 (0.59) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL31701364 0.81 ALDH1A1 (0.59) ALDH1A1KDM4EMAPTHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3495460-B1 GREASE COMPOSITION KYODO YUSHI (JP) 2024-03-06 EP claimed
US-11162051-B2 Grease composition KYODO YUSHI CO., LTD. (JP) 2021-11-02 US claimed
US-20190177645-A1 GREASE COMPOSITION KYODO YUSHI CO., LTD. (JP) 2019-06-13 US claimed
EP-3495460-A1 GREASE COMPOSITION Kyodo Yushi Co., Ltd. (JP) 2019-06-12 EP claimed
EP-0694057-B1 LUBRICANT COMPOSITION CONTAINING ANTIOXIDANT UNIROYAL CHEM CO INC (US) 2000-03-01 EP claimed
EP-0694057-A1 LUBRICANT COMPOSITION CONTAINING ANTIOXIDANT UNIROYAL CHEMICAL COMPANY, Inc. (US) 1996-01-31 EP claimed
WO-1994024235-A1 LUBRICANT COMPOSITION CONTAINING ANTIOXIDANT UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-10-27 WO claimed
US-5310491-A Alkyl substituted 1,2-dihydroquinoline reacted with diarylamine UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-05-10 US claimed
EP-3495460-B1 GREASE COMPOSITION KYODO YUSHI (JP) 2024-03-06 EP disclosed
US-11162051-B2 Grease composition KYODO YUSHI CO., LTD. (JP) 2021-11-02 US disclosed
US-20190177645-A1 GREASE COMPOSITION KYODO YUSHI CO., LTD. (JP) 2019-06-13 US disclosed
EP-3495460-A1 GREASE COMPOSITION Kyodo Yushi Co., Ltd. (JP) 2019-06-12 EP disclosed
US-20160312033-A1 DIARYLETHER-BASED FLUOROGENIC PROBES FOR DETECTION OF HYPOCHLOROUS ACID OR HYDROXYL RADICAL VERSITECH LIMITED (HK) 2016-10-27 US disclosed
US-20160311846-A1 FLUORESCENT DYES AND METHODS OF USE THEREOF ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) 2016-10-27 US disclosed
US-4326061-A ULTRAVIOLET RADIATION, STABILIZERS THE B. F. GOODRICH COMPANY (US) 1982-04-20 US disclosed
US-4247664-A Polymeric alkylated 1,2 dihydroquinolines THE B. F. GOODRICH COMPANY (US) 1981-01-27 US disclosed
US-4073770-A Substituted decahydroquinolines and their use as ultraviolet light stabilizers THE B. F. GOODRICH COMPANY (US) 1978-02-14 US disclosed
US-4069195-A FOR POLYOLEFINS THE B.F. GOODRICH COMPANY (US) 1978-01-17 US disclosed
US-4046765-A Dihydroquinoline derivatives of antioxidant activity and a process for the preparation thereof MATERIAL KSZ. (HU) 1977-09-06 US disclosed
US-4025631-A Dihydroquinoline derivatives of antioxidant activity MATERIAL KSZ. (HU) 1977-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160311846-A1 FLUORESCENT DYES AND METHODS OF USE THEREOF BCDIN3D, EFTUD2, IK ALDH1A1 245/4885KDM4E 2855/4885MAPT 4040/4885
US-20160312033-A1 DIARYLETHER-BASED FLUOROGENIC PROBES FOR DETECTION OF HYPOCHLOROUS ACID OR HYDROXYL RADICAL HAGH, HADH, FECH ALDH1A1 334/4885KDM4E 1598/4885MAPT 4173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.