SCHEMBL9415969

SCHEMBL9415969

CCCCCCCCC(CCO)CNCc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 1/20 0.45
EPHX2 P34913 2/20 0.44
S1PR2 O95136 3/20 0.44
S1PR4 O95977 3/20 0.44
S1PR1 P21453 3/20 0.44
S1PR3 Q99500 3/20 0.44
CSNK1E P49674 1/20 0.43
CNR2 P34972 1/20 0.43
TLR2 O60603 1/20 0.42
MAOA P21397 1/20 0.41
SPHK1 Q9NYA1 1/20 0.40
CHRM2 P08172 1/20 0.40
SIGMAR1 Q99720 1/20 0.40
LMNA P02545 1/20 0.40
FAAH O00519 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11143978 0.91 MAOA (0.46) KDM4EALDH1A1EPHX2S1PR2S1PR4
SCHEMBL14397621 0.90 LMNA (0.49) KDM4EALDH1A1EPHX2S1PR2S1PR4
SCHEMBL23665707 0.87 ALDH1A1 (0.55) KDM4EALDH1A1EPHX2S1PR2S1PR4
SCHEMBL7603827 0.85 ALDH1A1 (0.56) KDM4EALDH1A1EPHX2S1PR2S1PR4
SCHEMBL7605067 0.83 ALDH1A1 (0.50) KDM4EALDH1A1EPHX2S1PR2S1PR4
SCHEMBL9463779 0.81 S1PR2 (0.57) ALDH1A1EPHX2S1PR2S1PR4S1PR1
SCHEMBL11120188 0.81 S1PR2 (0.57) ALDH1A1EPHX2S1PR2S1PR4S1PR1
SCHEMBL28456149 0.81 S1PR2 (0.57) ALDH1A1EPHX2S1PR2S1PR4S1PR1
SCHEMBL3400591 0.80 ALDH1A1 (0.61) KDM4EALDH1A1S1PR2S1PR4S1PR1
SCHEMBL10712989 0.80 CSNK1E (0.56) CSNK1ECNR2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0599265-A1 Antibacterial, antifungal compound and its production method Takeda Chemical Industries, Ltd. (JP) 1994-06-01 EP disclosed