Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | STK10 | O94804 | 1/20 | 0.30 |
| ▸ | CLK2 | P49760 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119171 | 0.82 | CASP3 (0.36) | CASP3DDB1CRBN | |
| SCHEMBL8132902 | 0.81 | AR (0.34) | CASP3DDB1CRBNSTK10CLK2 | |
| SCHEMBL8128162 | 0.79 | CASP3 (0.34) | CASP3DDB1CRBN | |
| SCHEMBL8132547 | 0.78 | CYP1A2 (0.34) | CASP3DDB1CRBN | |
| SCHEMBL8134794 | 0.77 | RARG (0.35) | CASP3DDB1CRBN | |
| SCHEMBL8167098 | 0.76 | GAA (0.34) | CASP3DDB1CRBN | |
| SCHEMBL7966848 | 0.76 | CASP3 (0.30) | CASP3 | |
| SCHEMBL9416182 | 0.75 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL9416181 | 0.72 | ADORA2A (0.32) | — | |
| SCHEMBL7967343 | 0.67 | FABP4 (0.38) | CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0628562-A1 | Cephalospornis having in position 7 as substituted axymino radical, intermediates, processes for their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 1994-12-14 | — | — | EP | disclosed |