Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.35 |
| ▸ | ITGAL | P20701 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416351 | 0.91 | AURKA (0.38) | AURKAGSK3BNPC1RAB9AMITF | |
| SCHEMBL9416345 | 0.78 | PIK3CG (0.36) | AURKAGSK3BPKMITGB2ICAM1 | |
| SCHEMBL9198711 | 0.77 | AURKA (0.38) | AURKAGSK3BNPC1RAB9AMITF | |
| SCHEMBL9416363 | 0.75 | NOTUM (0.37) | ITGB2ICAM1ITGALMAPTMEN1 | |
| SCHEMBL9416357 | 0.74 | LMNA (0.35) | ITGB2ICAM1ITGALTHRBSMN1; SMN2 | |
| SCHEMBL9416336 | 0.72 | ITGB2 (0.47) | ITGB2ICAM1ITGALGAAMAPT | |
| SCHEMBL9416401 | 0.72 | NOTUM (0.41) | HPGDITGB2ICAM1ITGALTHRB | |
| SCHEMBL9416350 | 0.70 | FBP1 (0.43) | NPC1RAB9AHPGDSMN1; SMN2POLB | |
| SCHEMBL9416361 | 0.70 | ALDH1A1 (0.38) | NPC1RAB9AHPGDITGB2ICAM1 | |
| SCHEMBL9416342 | 0.70 | TSHR (0.41) | NPC1RAB9APKMITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627423-A1 | SUBSTITUTED PYRAZOLE DERIVATIVE AND AGROHORTICULTURAL BACTERICIDE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1994-12-07 | — | — | EP | disclosed |