Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.50 |
| ▸ | VDR | P11473 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | HTR6 | P50406 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3978103 | 0.86 | LMNA (0.58) | LMNAMAPK1MEN1KMT2AGAA | |
| SCHEMBL11694118 | 0.85 | ALDH1A1 (0.59) | LMNAMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL3824499 | 0.84 | LMNA (0.59) | LMNAMAPK1MEN1KMT2AGAA | |
| SCHEMBL29586241 | 0.84 | LMNA (0.59) | LMNAMAPK1MEN1KMT2AGAA | |
| SCHEMBL6938252 | 0.82 | ALDH1A1 (0.61) | LMNAMAPK1MEN1KMT2AGAA | |
| SCHEMBL3841625 | 0.81 | LMNA (0.54) | LMNAMAPK1MEN1KMT2AGAA | |
| SCHEMBL2983828 | 0.81 | HSD11B1 (0.54) | LMNAMAPK1MEN1KMT2AGAA | |
| SCHEMBL8132928 | 0.81 | LMNA (0.56) | LMNAMAPK1MEN1KMT2AGAA | |
| SCHEMBL2516102 | 0.81 | LMNA (0.56) | LMNAMAPK1MEN1KMT2AGAA | |
| SCHEMBL4120837 | 0.81 | LMNA (0.56) | LMNAMAPK1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178585-B2 | Solvent-free synthesis of soluble nanocrystals | ADVANCED TECHNOLOGY MATERIALS, INC. (US) | 2012-05-15 | — | — | US | claimed |
| US-20110006269-A1 | SOLVENT-FREE SYNTHESIS OF SOLUBLE NANOCRYSTALS | ADVANCED TECHNOLOGY MATERIALS, INC. (US) | 2011-01-13 | — | — | US | claimed |
| EP-2227319-A2 | SOLVENT-FREE SYNTHESIS OF SOLUBLE NANOCRYSTALS | Advanced Technology Materials, Inc. (US) | 2010-09-15 | — | — | EP | claimed |
| WO-2009065010-A2 | SOLVENT-FREE SYNTHESIS OF SOLUBLE NANOCRYSTALS | ADVANCED TECHNOLOGY MATERIALS, INC. (US) | 2009-05-22 | — | — | WO | claimed |
| US-8178585-B2 | Solvent-free synthesis of soluble nanocrystals | ADVANCED TECHNOLOGY MATERIALS, INC. (US) | 2012-05-15 | — | — | US | disclosed |
| US-20110006269-A1 | SOLVENT-FREE SYNTHESIS OF SOLUBLE NANOCRYSTALS | ADVANCED TECHNOLOGY MATERIALS, INC. (US) | 2011-01-13 | — | — | US | disclosed |
| EP-2227319-A2 | SOLVENT-FREE SYNTHESIS OF SOLUBLE NANOCRYSTALS | Advanced Technology Materials, Inc. (US) | 2010-09-15 | — | — | EP | disclosed |
| WO-2009065010-A2 | SOLVENT-FREE SYNTHESIS OF SOLUBLE NANOCRYSTALS | ADVANCED TECHNOLOGY MATERIALS, INC. (US) | 2009-05-22 | — | — | WO | disclosed |
| US-7118727-B2 | Method of making oxide particles | GENERAL ELECTRIC COMPANY (US) | 2006-10-10 | — | — | US | disclosed |
| US-20060133978-A1 | Method of making crystalline inorganic particles | GENERAL ELECTRIC COMPANY | 2006-06-22 | — | — | US | disclosed |
| US-20040253174-A1 | Method of making oxide particles | GENERAL ELECTRIC COMPANY | 2004-12-16 | — | — | US | disclosed |