Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612798 | 0.87 | IGF1R (0.53) | SLC6A3DRD2DRD4DRD3SLC6A4 | |
| SCHEMBL7755959 | 0.87 | SLC6A3 (0.50) | SLC6A3DRD2DRD4DRD3SLC6A4 | |
| Hydrochloric Acid SCHEMBL7543310 | 0.86 | SLC6A3 (0.49) | SLC6A3DRD2DRD4DRD3SLC6A4 | |
| SCHEMBL7754375 | 0.85 | IGF1R (0.55) | SLC6A3DRD2DRD3SLC6A4ACHE | |
| Hydrochloric Acid SCHEMBL7548578 | 0.84 | IGF1R (0.54) | SLC6A3DRD2DRD3SLC6A4ACHE | |
| SCHEMBL7751327 | 0.83 | SLC6A3 (0.54) | SLC6A3DRD2DRD4DRD3SLC6A4 | |
| Hydrochloric Acid SCHEMBL7544797 | 0.83 | SLC6A3 (0.53) | SLC6A3DRD2DRD4DRD3SLC6A4 | |
| SCHEMBL4760958 | 0.81 | CYP3A4 (0.51) | SLC6A3DRD2DRD4DRD3SLC6A4 | |
| SCHEMBL8616378 | 0.81 | CYP3A4 (0.51) | SLC6A3DRD2DRD4DRD3SLC6A4 | |
| SCHEMBL8615736 | 0.81 | CYP3A4 (0.51) | SLC6A3DRD2DRD4DRD3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612738-A1 | Diphenylpiperazine derivative and drug for circulatory organ containing the same | POLA CHEMICAL INDUSTRIES, INC. (JP) | 1994-08-31 | — | — | EP | disclosed |