Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637097 | 0.91 | MEN1 (0.61) | IGF1RMEN1KMT2AATMDNM1 | |
| SCHEMBL9416485 | 0.87 | SLC6A3 (0.45) | IGF1RMEN1KMT2AATMDNM1 | |
| SCHEMBL7751327 | 0.84 | SLC6A3 (0.54) | MEN1KMT2ADNM1OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL7544797 | 0.83 | SLC6A3 (0.53) | MEN1KMT2ADNM1OPRM1OPRD1 | |
| SCHEMBL7754375 | 0.83 | IGF1R (0.55) | IGF1RMEN1KMT2AATMOPRM1 | |
| SCHEMBL7439416 | 0.83 | IGF1R (0.57) | IGF1RMEN1KMT2AATMOPRM1 | |
| Hydrochloric Acid SCHEMBL7548578 | 0.82 | IGF1R (0.54) | IGF1RMEN1KMT2AATMOPRM1 | |
| SCHEMBL7435733 | 0.80 | IGF1R (0.60) | IGF1RMEN1KMT2AATMOPRM1 | |
| SCHEMBL24322660 | 0.79 | MEN1 (0.58) | IGF1RMEN1KMT2AATMOPRM1 | |
| SCHEMBL8612921 | 0.79 | MEN1 (0.58) | IGF1RMEN1KMT2AATMOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549796-B1 | DIPHENYLPIPERAZINE DERIVATIVE AND DRUG FOR CIRCULATORY ORGAN CONTAINING THE SAME | POLA CHEM IND INC (JP) | 1998-04-29 | — | — | EP | disclosed |
| US-5391552-A | Has strong antagonism against calcium with less side effects | POLA CHEMICAL INDUSTRIES, INC. (JP) | 1995-02-21 | — | — | US | disclosed |
| EP-0549796-A1 | DIPHENYLPIPERAZINE DERIVATIVE AND DRUG FOR CIRCULATORY ORGAN CONTAINING THE SAME | POLA CHEMICAL INDUSTRIES INC (JP) | 1993-07-07 | — | — | EP | disclosed |