Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28099468 | 0.80 | EIF2AK2 (0.33) | EIF2AK2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL11358290 | 0.79 | EIF2AK2 (0.33) | EIF2AK2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6361568 | 0.75 | EIF2AK2 (0.30) | EIF2AK2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL5704099 | 0.74 | EIF2AK2 (0.32) | EIF2AK2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL709530 | 0.74 | ALDH1A1 (0.31) | — | |
| SCHEMBL4601312 | 0.70 | EIF2AK2 (0.32) | EIF2AK2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL4600851 | 0.69 | TP53 (0.35) | — | |
| SCHEMBL4599386 | 0.68 | TDP1 (0.41) | — | |
| SCHEMBL6686565 | 0.68 | TDP1 (0.34) | EIF2AK2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL9464954 | 0.67 | TDP1 (0.33) | EIF2AK2CSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390042-B1 | Process for the preparation of bromosubstituted aromatic esters of alfa,beta unsaturated acids | BROMINE COMPOUNDS LTD (IL) | 1994-01-19 | — | — | EP | claimed |
| US-5072028-A | Process for the preparation of bromo-substituted aromatic esters of α,β-unsaturated acids | BROMINE COMPOUNDS LIMITED (IL) | 1991-12-10 | — | — | US | claimed |
| EP-0390042-A1 | Process for the preparation of bromosubstituted aromatic esters of alfa,beta unsaturated acids | Bromine Compounds Ltd. (IL) | 1990-10-03 | — | — | EP | claimed |