Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4599386 | 0.77 | TDP1 (0.41) | TDP1 | |
| SCHEMBL5847630 | 0.72 | TDP1 (0.37) | TDP1 | |
| SCHEMBL11358290 | 0.70 | EIF2AK2 (0.33) | TDP1EIF2AK2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL328794 | 0.69 | TDP1 (0.40) | TDP1EIF2AK2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL4455527 | 0.69 | TDP1 (0.40) | TDP1EIF2AK2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL5704099 | 0.69 | EIF2AK2 (0.32) | TDP1EIF2AK2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL2928223 | 0.69 | TDP1 (0.31) | TDP1 | |
| SCHEMBL9416552 | 0.68 | EIF2AK2 (0.35) | EIF2AK2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6361568 | 0.67 | EIF2AK2 (0.30) | EIF2AK2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL27777163 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100448840-C | Brominated esters, methods for their preparation and use thereof as flame retardants | BROMINE COMPOUNDS LTD (IL) | 2009-01-07 | — | — | CN | disclosed |
| CN-1646471-A | Brominated esters, methods for their preparation and use thereof as flame retardants | BROMINE COMPOUNDS LTD (IL) | 2005-07-27 | — | — | CN | disclosed |
| EP-1478615-A1 | BROMINATED ESTERS, METHODS FOR THEIR PREPARATION AND USE THEREOF AS FLAME RETARDANTS | Bromine Compounds Ltd. (IL) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003070685-A1 | BROMINATED ESTERS, METHODS FOR THEIR PREPARATION AND USE THEREOF AS FLAME RETARDANTS | BROMINE COMPOUNDS LTD. (IL) | 2003-08-28 | — | — | WO | disclosed |