Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5847630 | 0.80 | TDP1 (0.37) | TDP1AKR1B1 | |
| SCHEMBL328794 | 0.77 | TDP1 (0.40) | TDP1AKR1B1APEX1 | |
| SCHEMBL4455527 | 0.77 | TDP1 (0.40) | TDP1AKR1B1APEX1 | |
| SCHEMBL6686565 | 0.77 | TDP1 (0.34) | TDP1 | |
| SCHEMBL11663568 | 0.74 | TDP1 (0.32) | TDP1 | |
| SCHEMBL11358290 | 0.74 | EIF2AK2 (0.33) | TDP1 | |
| SCHEMBL5186322 | 0.73 | TDP1 (0.37) | TDP1APEX1 | |
| SCHEMBL4601560 | 0.73 | TDP1 (0.37) | TDP1AKR1B1APEX1 | |
| SCHEMBL2882117 | 0.73 | TDP1 (0.37) | TDP1APEX1MAPTNPSR1 | |
| SCHEMBL9373547 | 0.73 | TDP1 (0.37) | TDP1APEX1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103987811-B | Fire retardant, its preparation method and its purposes in polyurethane and polyisocyanurate foam | 溴化合物有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-103987811-A | Flame retardants, processes for their preparation and uses thereof in polyurethane and polyisocyanurate foams | BROMINE COMPOUNDS LTD | 2014-08-13 | — | — | CN | disclosed |
| EP-1470097-B1 | PENTABROMOBENZYL ALKYL ETHERS AND THEIR USE AS FIRE RETARDANTS | BROMINE COMPOUNDS LTD (IL) | 2008-04-16 | — | — | EP | disclosed |
| CN-1319923-C | Pentabromobenzyl alkyl ethers and their use as fire retardants | BROMINE COMPOUNDS LTD (IL) | 2007-06-06 | — | — | CN | disclosed |
| EP-1773934-A2 | NOVEL FIRE RETARDANTS | Bromine Compounds Ltd. (IL) | 2007-04-18 | — | — | EP | disclosed |
| US-7091270-B2 | Pentabromobenzyl alkyl ethers and their use as fire retardants | BROMINE COMPOUNDS LTD. (IL) | 2006-08-15 | — | — | US | disclosed |
| WO-2006006154-A2 | NOVEL FIRE RETARDANTS | BROMINE COMPOUNDS LTD. (IL) | 2006-01-19 | — | — | WO | disclosed |
| US-20050124746-A1 | Pentabromobenzyl alkyl ethers and their use as fire retardants | BROMINE COMPOUNDS LTD. (IL) | 2005-06-09 | — | — | US | disclosed |
| CN-1625540-A | Pentabromobenzyl alkyl ethers and their use as fire retardants | BROMINE COMPOUNDS LTD (IL) | 2005-06-08 | — | — | CN | disclosed |
| EP-1470097-A1 | PENTABROMOBENZYL ALKYL ETHERS AND THEIR USE AS FIRE RETARDANTS | Bromine Compounds Ltd. (IL) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064361-A1 | PENTABROMOBENZYL ALKYL ETHERS AND THEIR USE AS FIRE RETARDANTS | BROMINE COMPOUNDS LTD. (IL) | 2003-08-07 | — | — | WO | disclosed |