Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.55 |
| ▸ | MMP2 | P08253 | 2/20 | 0.55 |
| ▸ | MMP3 | P08254 | 2/20 | 0.55 |
| ▸ | MMP9 | P14780 | 2/20 | 0.55 |
| ▸ | MMP12 | P39900 | 2/20 | 0.55 |
| ▸ | MMP13 | P45452 | 2/20 | 0.55 |
| ▸ | LDHA | P00338 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | F7 | P08709 | 1/20 | 0.51 |
| ▸ | F3 | P13726 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416607 | 0.90 | APP (0.51) | MMP1MMP2MMP3MMP9MMP12 | |
| SCHEMBL28611663 | 0.84 | PPARA (0.64) | MMP1MMP2MMP3MMP9MMP12 | |
| SCHEMBL8964099 | 0.82 | MMP1 (0.57) | MMP1MMP2MMP3MMP9MMP12 | |
| SCHEMBL6373010 | 0.82 | HPGD (0.56) | SMPD1HDAC1HDAC8HDAC6APP | |
| SCHEMBL7962440 | 0.82 | HPGD (0.56) | SMPD1HDAC1HDAC8HDAC6APP | |
| SCHEMBL7962444 | 0.82 | HPGD (0.56) | SMPD1HDAC1HDAC8HDAC6APP | |
| SCHEMBL8964094 | 0.82 | MMP1 (0.57) | MMP1MMP2MMP3MMP9MMP12 | |
| SCHEMBL7823960 | 0.82 | SMPD1 (0.57) | MMP1MMP2MMP3MMP9MMP12 | |
| SCHEMBL5041809 | 0.81 | SMPD1 (0.56) | MMP1MMP2MMP3MMP9MMP12 | |
| SCHEMBL4658405 | 0.81 | LDHA (0.64) | MMP1LDHAALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613879-A1 | PHELLODENDRINE ANALOGS AND ALLERGY TYPE IV SUPPRESSOR CONTAINING THE SAME AS ACTIVE INGREDIENT | TSUMURA & CO. (JP) | 1994-09-07 | — | — | EP | disclosed |