Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | NPC1 | O15118 | 1/20 | 0.76 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.61 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.61 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.61 |
| ▸ | GPR183 | P32249 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8436351 | 0.85 | KMT2A (0.58) | KMT2ANPC1ABCB1ABCC1CHRNA7 | |
| SCHEMBL8439752 | 0.85 | KMT2A (0.58) | KMT2ANPC1ABCB1ABCC1GPR183 | |
| SCHEMBL9668362 | 0.85 | CHRNA7 (0.69) | KMT2ANPC1CHRNA7GPR183HCRTR2 | |
| SCHEMBL9667825 | 0.85 | CHRNA7 (0.69) | KMT2ANPC1CHRNA7GPR183HCRTR2 | |
| SCHEMBL9416605 | 0.84 | LMNA (0.75) | KMT2ANPC1CHRNA7GPR183SMN1; SMN2 | |
| SCHEMBL5096699 | 0.83 | KMT2A (0.86) | KMT2ANPC1ABCB1ABCC1GPR183 | |
| SCHEMBL3056571 | 0.81 | KDM4E (0.69) | KMT2ANPC1ABCB1CHRNA7GPR183 | |
| SCHEMBL8437814 | 0.81 | KMT2A (0.52) | KMT2ANPC1ABCB1ABCC1GPR183 | |
| SCHEMBL8437426 | 0.81 | KMT2A (0.52) | KMT2ANPC1ABCB1ABCC1CHRNA7 | |
| SCHEMBL8791190 | 0.81 | KMT2A (0.71) | KMT2ANPC1ABCB1ABCC1GPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613879-A1 | PHELLODENDRINE ANALOGS AND ALLERGY TYPE IV SUPPRESSOR CONTAINING THE SAME AS ACTIVE INGREDIENT | TSUMURA & CO. (JP) | 1994-09-07 | — | — | EP | disclosed |