Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 3/20 | 0.67 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.59 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637846 | 0.92 | MTNR1B (0.64) | MTNR1BHCRTR1HCRTR2PDE4DLMNA | |
| SCHEMBL31538834 | 0.90 | LMNA (0.68) | MTNR1BHCRTR1HCRTR2PDE4DLMNA | |
| SCHEMBL13064945 | 0.90 | LMNA (0.68) | MTNR1BHCRTR1HCRTR2PDE4DLMNA | |
| SCHEMBL30585089 | 0.85 | LMNA (0.79) | LMNA | |
| SCHEMBL9637922 | 0.85 | LMNA (0.61) | MTNR1BHCRTR1HCRTR2PDE4DLMNA | |
| SCHEMBL9585990 | 0.85 | LMNA (0.79) | LMNA | |
| SCHEMBL5097146 | 0.85 | MTNR1B (0.70) | MTNR1BHCRTR1HCRTR2PDE4D | |
| SCHEMBL29059153 | 0.83 | HCRTR1 (0.62) | HCRTR1HCRTR2LMNA | |
| SCHEMBL17821870 | 0.82 | MTNR1B (0.60) | MTNR1BLMNAMAPT | |
| SCHEMBL3506766 | 0.82 | MTNR1B (0.69) | MTNR1BHCRTR1HCRTR2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613879-A1 | PHELLODENDRINE ANALOGS AND ALLERGY TYPE IV SUPPRESSOR CONTAINING THE SAME AS ACTIVE INGREDIENT | TSUMURA & CO. (JP) | 1994-09-07 | — | — | EP | disclosed |