Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TEK | Q02763 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416700 | 0.94 | TEK (0.53) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9416868 | 0.86 | MAPT (0.52) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| Potassium Ion SCHEMBL10627093 | 0.86 | MAPT (0.55) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL10627131 | 0.86 | MAPT (0.55) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL10626101 | 0.82 | MAPT (0.49) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL1259692 | 0.82 | LMNA (0.47) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL10627119 | 0.80 | RAB9A (0.50) | MAPTMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL10631449 | 0.79 | NPC1 (0.46) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL3440627 | 0.79 | ALDH1A1 (0.59) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9416860 | 0.78 | MAPT (0.47) | MAPTMEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4736056-A | Process for the production of malonic acid derivative compounds | UNION CARBIDE AGRICULTURAL PRODUCTS COMPANY, INC., T.W. ALEXANDER DR., RESEARCH TRIANGLE PARK, NC. A CORP. OF PA. | 1988-04-05 | — | — | US | claimed |
| US-5292937-A | Use of malonic acid derivative compounds for retarding plant growth | RHONE-POULENC INC. (US) | 1994-03-08 | — | — | US | disclosed |
| US-5123951-A | Ethylene response inducing agent and malonic acid derivative | RHONE-POULENC NEDERLAND B.V. (NL) | 1992-06-23 | — | — | US | disclosed |
| US-4736056-A | Process for the production of malonic acid derivative compounds | UNION CARBIDE AGRICULTURAL PRODUCTS COMPANY, INC., T.W. ALEXANDER DR., RESEARCH TRIANGLE PARK, NC. A CORP. OF PA. | 1988-04-05 | — | — | US | disclosed |