Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416748 | 0.84 | SLC6A4 (0.41) | SLC6A4SLC6A3ALDH1A1MEN1KMT2A | |
| SCHEMBL15601014 | 0.76 | KMT2A (0.52) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL9238358 | 0.75 | TDP1 (0.45) | ALDH1A1MEN1KMT2AKDM4EOPRM1 | |
| SCHEMBL5682343 | 0.75 | SMN1; SMN2 (0.44) | SLC6A4ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL5682090 | 0.70 | OPRM1 (0.50) | SLC6A4ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5678261 | 0.70 | KMT2A (0.46) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL28762313 | 0.69 | TSHR (0.42) | ALDH1A1KMT2AKDM4EHPGDLMNA | |
| SCHEMBL7536487 | 0.69 | SLC6A4 (0.61) | SLC6A4SLC6A3MEN1KMT2ALTB4R2 | |
| SCHEMBL15348156 | 0.69 | MEN1 (0.47) | ALDH1A1MEN1KMT2ALMNAPRKCZ | |
| SCHEMBL9768195 | 0.67 | ABCB11 (0.54) | MEN1KMT2AKDM4ELMNAOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292937-A | Use of malonic acid derivative compounds for retarding plant growth | RHONE-POULENC INC. (US) | 1994-03-08 | — | — | US | disclosed |
| US-5123951-A | Ethylene response inducing agent and malonic acid derivative | RHONE-POULENC NEDERLAND B.V. (NL) | 1992-06-23 | — | — | US | disclosed |