Methane

Methane

SCHEMBL9416768

C.NC(=O)NNS(=O)(=O)O

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.33
NFKB1 P19838 2/20 0.33
LMNA P02545 2/20 0.33
BLM P54132 2/20 0.33
CA2 P00918 2/20 0.33
CA5A P35218 2/20 0.33
CA9 Q16790 2/20 0.33
CYP1A2 P05177 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
THPO P40225 1/20 0.33
CYP3A4 P08684 1/20 0.33
PMP22 Q01453 1/20 0.33
KDM4E B2RXH2 1/20 0.30
CA1 P00915 1/20 0.30
NT5E P21589 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
CA7 P43166 1/20 0.30
CA5B Q9Y2D0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2236617 0.97
Benzene SCHEMBL9416754 0.90 MEN1 (0.35) TSHRNFKB1LMNABLMCA2
Isobutane SCHEMBL9416819 0.87 CA14 (0.32)
SCHEMBL28673580 0.77 TSHR (0.37) TSHRNFKB1LMNABLMCA2
Toluene SCHEMBL7587487 0.76 LMNA (0.44) TSHRLMNACYP1A2CYP3A4KDM4E
SCHEMBL2301513 0.74
SCHEMBL2782941 0.72
SCHEMBL21785 0.71
Ammonia Solution, Strong SCHEMBL28267901 0.70 ALDH1A1 (0.45) CA2CA5A
SCHEMBL27521285 0.70 TSHR (0.33) TSHRNFKB1LMNABLMCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0407886-B1 Method for producing plastic hollow parts with foamed walls HOECHST AG (DE) 1994-02-23 EP disclosed
EP-0407886-A2 Method for producing plastic hollow parts with foamed walls HOECHST AKTIENGESELLSCHAFT (DE) 1991-01-16 EP disclosed