Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416753 | 0.93 | ALDH1A1 (0.49) | ALDH1A1HPGDGAASMN1; SMN2MAPT | |
| SCHEMBL9416757 | 0.87 | GAA (0.44) | ALDH1A1HPGDGAASMN1; SMN2MAPT | |
| SCHEMBL9723194 | 0.84 | ALDH1A1 (0.42) | ALDH1A1HPGDGAASMN1; SMN2MAPT | |
| SCHEMBL8179045 | 0.80 | OPRK1 (0.47) | ALDH1A1HPGDGAASMN1; SMN2MAPT | |
| SCHEMBL26862448 | 0.78 | ALDH1A1 (0.45) | ALDH1A1HPGDGAASMN1; SMN2MAPT | |
| SCHEMBL18663359 | 0.77 | ALDH1A1 (0.43) | ALDH1A1HPGDGAASMN1; SMN2MAPT | |
| SCHEMBL26792532 | 0.77 | ALDH1A1 (0.48) | ALDH1A1HPGDGAASMN1; SMN2MAPT | |
| SCHEMBL19690389 | 0.76 | SMN1; SMN2 (0.40) | ALDH1A1HPGDGAASMN1; SMN2MAPT | |
| SCHEMBL26862446 | 0.76 | OPRM1 (0.48) | ALDH1A1HPGDGAASMN1; SMN2MAPT | |
| SCHEMBL26792521 | 0.74 | ALDH1A1 (0.46) | ALDH1A1HPGDGAASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292937-A | Use of malonic acid derivative compounds for retarding plant growth | RHONE-POULENC INC. (US) | 1994-03-08 | — | — | US | disclosed |
| US-5123951-A | Ethylene response inducing agent and malonic acid derivative | RHONE-POULENC NEDERLAND B.V. (NL) | 1992-06-23 | — | — | US | disclosed |