Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 3/20 | 0.38 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | FDPS | P14324 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417030 | 0.75 | MEN1 (0.33) | MEN1KMT2ATSHR | |
| SCHEMBL6351937 | 0.74 | GABBR2 (0.50) | GABBR2GABBR1GABRR1CYP1A2MEN1 | |
| Hydrochloric Acid SCHEMBL9417053 | 0.72 | GABBR2 (0.48) | GABBR2GABBR1GABRR1CYP1A2MEN1 | |
| Hydrochloric Acid SCHEMBL2422434 | 0.70 | PNP (0.41) | GABBR2GABBR1CYP1A2MEN1KMT2A | |
| SCHEMBL15041913 | 0.70 | TSHR (0.40) | TSHRLPAR1LPAR3FDPSCYP3A4 | |
| SCHEMBL491488 | 0.68 | PPARD (0.54) | GABBR2GABBR1GABRR1CYP1A2MEN1 | |
| SCHEMBL15798054 | 0.67 | PNP (0.39) | TSHRLPAR1LPAR3LMNAFDPS | |
| SCHEMBL9062818 | 0.67 | GABBR2 (0.55) | GABBR2GABBR1GABRR1CYP1A2MEN1 | |
| SCHEMBL5669782 | 0.65 | CYP1A2 (0.44) | GABBR2GABBR1GABRR1CYP1A2MEN1 | |
| SCHEMBL13725451 | 0.65 | PPARD (0.59) | GABBR2GABBR1GABRR1CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300679-A | Antagonists to 4-aminobutyric acid | CIBA-GEIGY CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |
| US-5190933-A | Treatment of cognitive and memory disorders | CIBA-GEIGY CORPORATION (US) | 1993-03-02 | — | — | US | disclosed |
| US-5064819-A | Antidepressants, anxiolytic agents, GABA antagonists | CIBA-GEIGY CORPORATION (US) | 1991-11-12 | — | — | US | disclosed |
| US-5051524-A | Treatment of a phosphinic acid with an anhydrous protic medium | CIBA-GEIGY CORPORATION (US) | 1991-09-24 | — | — | US | disclosed |
| US-5013863-A | Learning enhancement | CIBA-GEIGY CORPORATION (US) | 1991-05-07 | — | — | US | disclosed |