Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416951 | 0.75 | GABBR2 (0.38) | MEN1KMT2ATSHR | |
| SCHEMBL9336342 | 0.73 | ACHE (0.34) | MEN1KMT2AACHETSHR | |
| SCHEMBL9359445 | 0.70 | ACHE (0.39) | MEN1KMT2AACHETSHR | |
| SCHEMBL15041913 | 0.69 | TSHR (0.40) | TSHR | |
| SCHEMBL491513 | 0.69 | TSHR (0.54) | MEN1KMT2AACHETSHR | |
| SCHEMBL7790759 | 0.67 | TSHR (0.41) | MEN1KMT2AACHETSHR | |
| SCHEMBL9063517 | 0.67 | TSHR (0.43) | MEN1KMT2AACHETSHR | |
| SCHEMBL11726422 | 0.66 | PPARD (0.57) | MEN1KMT2AACHETSHR | |
| SCHEMBL8971494 | 0.66 | ACHE (0.36) | MEN1KMT2AACHETSHR | |
| SCHEMBL19398541 | 0.65 | TSHR (0.48) | MEN1KMT2AACHETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300679-A | Antagonists to 4-aminobutyric acid | CIBA-GEIGY CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |
| US-5190933-A | Treatment of cognitive and memory disorders | CIBA-GEIGY CORPORATION (US) | 1993-03-02 | — | — | US | disclosed |
| US-5064819-A | Antidepressants, anxiolytic agents, GABA antagonists | CIBA-GEIGY CORPORATION (US) | 1991-11-12 | — | — | US | disclosed |
| US-5051524-A | Treatment of a phosphinic acid with an anhydrous protic medium | CIBA-GEIGY CORPORATION (US) | 1991-09-24 | — | — | US | disclosed |
| US-5013863-A | Learning enhancement | CIBA-GEIGY CORPORATION (US) | 1991-05-07 | — | — | US | disclosed |