Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417035 | 0.80 | MAPT (0.44) | MAPTCYP2C9CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL28326950 | 0.77 | MAPT (0.64) | MAPTCYP2C9CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9417061 | 0.74 | ALOX5 (0.40) | MAPTCYP2C9GAATSHRKDM4E | |
| SCHEMBL9417114 | 0.73 | ALOX5 (0.33) | — | |
| SCHEMBL9417032 | 0.73 | CYP2A13 (0.48) | MAPTCYP2C9CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL11279318 | 0.72 | MAPT (0.59) | MAPTCYP2C9CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9417026 | 0.71 | PTGS1 (0.37) | MAPTRAB9ANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18161774 | 0.70 | MAPT (0.52) | MAPTCYP2C9GAACYP2A13NOS1 | |
| SCHEMBL16119872 | 0.70 | MAPT (0.52) | MAPTCYP2C9CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL16119871 | 0.70 | MAPT (0.52) | MAPTCYP2C9CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358652-A | Using 3,5-dihydrocarbyl-4-hydroxybenzylamine compound | ETHYL PETROLEUM ADDITIVES, LIMITED (GB) | 1994-10-25 | — | — | US | disclosed |