Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.35 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416937 | 0.81 | HDAC4 (0.39) | PTGS1PTGS2ALOX5TTRHMGB1 | |
| SCHEMBL9417061 | 0.78 | ALOX5 (0.40) | PTGS1PTGS2ALOX5TTRHMGB1 | |
| SCHEMBL9417018 | 0.78 | ALOX5 (0.35) | PTGS1PTGS2ALOX5TTRNSD2 | |
| SCHEMBL9416981 | 0.77 | TTR (0.33) | PTGS1PTGS2ALOX5TTRHMGB1 | |
| SCHEMBL3634455 | 0.72 | MEN1 (0.40) | PTGS1PTGS2ALOX5TTRNISCH | |
| SCHEMBL3634451 | 0.72 | MEN1 (0.40) | PTGS1PTGS2ALOX5TTRNISCH | |
| SCHEMBL9417037 | 0.71 | MAPT (0.44) | NSD2MAPTLMNANPSR1L3MBTL1 | |
| SCHEMBL9417015 | 0.70 | PDCD1 (0.41) | PTGS1PTGS2ALOX5NSD2SCN2A | |
| SCHEMBL3640372 | 0.70 | PTGS1 (0.47) | PTGS1PTGS2ALOX5TTRNISCH | |
| SCHEMBL3640368 | 0.70 | PTGS1 (0.47) | PTGS1PTGS2ALOX5TTRNISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358652-A | Using 3,5-dihydrocarbyl-4-hydroxybenzylamine compound | ETHYL PETROLEUM ADDITIVES, LIMITED (GB) | 1994-10-25 | — | — | US | disclosed |