Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.64 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.64 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.54 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.54 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.54 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.54 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.54 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.54 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.54 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.54 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.54 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.54 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.54 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.54 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.54 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.54 |
| ▸ | PSMB3 | P49720 | 2/20 | 0.54 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.54 |
| ▸ | PSMA6 | P60900 | 2/20 | 0.54 |
| ▸ | PSMA8 | Q8TAA3 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417384 | 1.00 | SOAT2 (0.64) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL9171768 | 0.98 | SOAT2 (0.67) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL9171776 | 0.98 | SOAT2 (0.67) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL9168644 | 0.91 | SOAT2 (0.54) | SOAT2SOAT1MEN1KMT2AALDH1A1 | |
| SCHEMBL10710359 | 0.87 | SOAT2 (0.66) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL10710362 | 0.87 | SOAT2 (0.66) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL9162956 | 0.85 | EPHX2 (0.49) | SOAT2SOAT1CNR1CNR2MEN1 | |
| SCHEMBL16624603 | 0.85 | SOAT2 (0.62) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL18240159 | 0.82 | SOAT2 (0.94) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL469579 | 0.82 | SOAT2 (0.68) | SOAT2SOAT1PSMB11PSMA7PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5324747-A | Treatment of inflammatory diseases | HOFFMANN-LA ROCHE INC. (US) | 1994-06-28 | — | — | US | disclosed |