Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.68 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.68 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.60 |
| ▸ | CNR1 | P21554 | 5/20 | 0.60 |
| ▸ | FAAH | O00519 | 4/20 | 0.60 |
| ▸ | CNR2 | P34972 | 4/20 | 0.60 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.57 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.57 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.57 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.57 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.57 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.57 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.57 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.57 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.57 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.57 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.57 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.57 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.57 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL469464 | 0.99 | SOAT2 (0.66) | SOAT2SOAT1EPHX2CNR1FAAH | |
| SCHEMBL469516 | 0.98 | SOAT2 (0.71) | SOAT2SOAT1EPHX2CNR1FAAH | |
| SCHEMBL10077351 | 0.97 | SOAT2 (0.62) | SOAT2SOAT1EPHX2CNR1FAAH | |
| SCHEMBL469656 | 0.89 | EPHX2 (0.58) | SOAT2SOAT1EPHX2CNR1FAAH | |
| SCHEMBL18240159 | 0.84 | SOAT2 (0.94) | SOAT2SOAT1EPHX2CNR1FAAH | |
| SCHEMBL10077432 | 0.84 | SELP (0.55) | SOAT2SOAT1EPHX2CNR1FAAH | |
| SCHEMBL469507 | 0.84 | SELP (0.55) | SOAT2SOAT1EPHX2CNR1FAAH | |
| SCHEMBL454877 | 0.84 | SELP (0.55) | SOAT2SOAT1EPHX2CNR1FAAH | |
| SCHEMBL9206018 | 0.83 | SOAT2 (0.69) | SOAT2SOAT1EPHX2CNR1FAAH | |
| SCHEMBL29379899 | 0.82 | SOAT2 (1.00) | SOAT2SOAT1EPHX2CNR1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160120995-A1 | CONJUGATES OF POLYUNSATURATED FATTY ACIDS AND AMINE-CONTAINING COMPOUNDS AND USES THEREOF | MEDWELL LAB LTD (IL) | 2016-05-05 | — | — | US | disclosed |
| US-20160120995-A1 | CONJUGATES OF POLYUNSATURATED FATTY ACIDS AND AMINE-CONTAINING COMPOUNDS AND USES THEREOF | MEDWELL LAB LTD (IL) | 2016-05-05 | — | — | US | disclosed |
| US-20130158070-A1 | CONJUGATES OF POLYUNSATURATED FATTY ACIDS AND AMINE-CONTAINING COMPOUNDS AND USES THEREOF | MEDWELL LABORATORIES LTD. (IL) | 2013-06-20 | — | — | US | disclosed |
| US-20130158070-A1 | CONJUGATES OF POLYUNSATURATED FATTY ACIDS AND AMINE-CONTAINING COMPOUNDS AND USES THEREOF | MEDWELL LABORATORIES LTD. (IL) | 2013-06-20 | — | — | US | disclosed |
| WO-2012032509-A2 | CONJUGATES OF POLYUNSATURATED FATTY ACIDS AND AMINE-CONTAINING COMPOUNDS AND USES THEREOF | MEDWELL LABORATORIES LTD. (IL) | 2012-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158070-A1 | CONJUGATES OF POLYUNSATURATED FATTY ACIDS AND AMINE-CONTAINING COMPOUNDS AND USES THEREOF | ALOX5, ALOX15B, ALOX15 | SOAT2 148/4885SOAT1 371/4885EPHX2 99/4885 |
| US-20160120995-A1 | CONJUGATES OF POLYUNSATURATED FATTY ACIDS AND AMINE-CONTAINING COMPOUNDS AND USES THEREOF | ALOX5, ALOX15B, ALOX15 | SOAT2 151/4885SOAT1 364/4885EPHX2 91/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.