Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27352619 | 0.79 | TSHR (0.43) | ALDH1A1RAB9ANPC1HTTNPSR1 | |
| SCHEMBL8393230 | 0.76 | ALOX5 (0.44) | ALDH1A1NPSR1KMT2APDCD1CD274 | |
| SCHEMBL8393226 | 0.76 | TSHR (0.41) | ALDH1A1RAB9ANPC1HTTNPSR1 | |
| SCHEMBL27813706 | 0.75 | ALDH1A1 (0.42) | HPGDALDH1A1NPSR1KMT2APDCD1 | |
| SCHEMBL20766982 | 0.73 | ALDH1A1 (0.39) | ALDH1A1RAB9ANPC1HTTNPSR1 | |
| SCHEMBL4526462 | 0.72 | HPGD (0.50) | HPGDALDH1A1RAB9ANPC1HTT | |
| Acetic Acid SCHEMBL19639567 | 0.71 | TSHR (0.37) | ALDH1A1NPC1NPSR1MEN1KMT2A | |
| SCHEMBL30796294 | 0.71 | SMN1; SMN2 (0.50) | HPGDALDH1A1NPC1MEN1KMT2A | |
| Oxalic Acid SCHEMBL19639580 | 0.71 | TSHR (0.37) | ALDH1A1NPSR1MEN1KMT2AKDM4E | |
| Benzoic Acid SCHEMBL19639530 | 0.71 | TSHR (0.41) | ALDH1A1RAB9ANPC1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296601-A | Reaction of aromatic chloride with carbon monoxide and alcohol | NIHON NOHYAKU CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| US-5142057-A | Reacting an organic chloride with carbon monoxide and amine | NIHON NOHYAKU CO., LTD. (JP) | 1992-08-25 | — | — | US | disclosed |