Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27352619 | 0.82 | TSHR (0.43) | ALDH1A1TSHRSMN1; SMN2GAAPDCD1 | |
| SCHEMBL27813706 | 0.81 | ALDH1A1 (0.42) | ALDH1A1TSHRSMN1; SMN2GAAPDCD1 | |
| SCHEMBL7860796 | 0.80 | KMT2A (0.41) | ALDH1A1TSHRSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL8393226 | 0.79 | TSHR (0.41) | ALDH1A1TSHRSMN1; SMN2GAAPDCD1 | |
| SCHEMBL8393230 | 0.79 | ALOX5 (0.44) | ALDH1A1TSHRSMN1; SMN2GAAPDCD1 | |
| SCHEMBL9417465 | 0.73 | HPGD (0.46) | ALDH1A1SMN1; SMN2PDCD1CD274LMNA | |
| Acetic Acid SCHEMBL19639567 | 0.73 | TSHR (0.37) | ALDH1A1TSHRSMN1; SMN2GAAPDCD1 | |
| SCHEMBL30796294 | 0.73 | SMN1; SMN2 (0.50) | ALDH1A1TSHRSMN1; SMN2LMNAL3MBTL1 | |
| Oxalic Acid SCHEMBL19639580 | 0.73 | TSHR (0.37) | ALDH1A1TSHRSMN1; SMN2GAAPDCD1 | |
| Hydrochloric Acid SCHEMBL27617832 | 0.73 | PDK1 (0.38) | ALDH1A1SMN1; SMN2LMNAL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040106-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | claimed |