Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 8/20 | 0.38 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 7/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3033073 | 0.99 | LTB4R (0.41) | LTB4RTHRAPLA2G2DPPARGPPARD | |
| SCHEMBL9417814 | 0.94 | THRA (0.37) | LTB4RTHRAPLA2G2DTHRBNR1H4 | |
| SCHEMBL9417891 | 0.87 | MAPK1 (0.40) | MEN1LMNAKMT2ATHRB | |
| SCHEMBL10522356 | 0.81 | LTB4R (0.56) | LTB4RTHRAPLA2G2DTHRB | |
| SCHEMBL6935194 | 0.80 | LTB4R (0.46) | LTB4RTHRAPLA2G2DPPARGPPARD | |
| SCHEMBL9387348 | 0.79 | LTB4R (0.48) | LTB4RTHRAPLA2G2DTHRB | |
| SCHEMBL2422646 | 0.78 | LTB4R (0.45) | LTB4RTHRAPLA2G2DPPARGPPARD | |
| Hydrochloric Acid SCHEMBL9417918 | 0.78 | LTB4R (0.45) | LTB4RTHRAPLA2G2DPPARGPPARD | |
| SCHEMBL6136991 | 0.77 | LTB4R (0.44) | LTB4RTHRAPLA2G2DPPARGPPARD | |
| SCHEMBL8777238 | 0.77 | LTB4R (0.44) | LTB4RTHRAPLA2G2DPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294613-A | Benzene derivatives of p-substituted ether and acid or ester | ELI LILLY AND COMPANY (US) | 1994-03-15 | — | — | US | disclosed |
| US-5098613-A | Aromatic ethers for treatment of mammals | ELI LILLY AND COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-4945099-A | LEUKOTRIENE ANTAGONIST | ELI LILLY AND COMPANY (US) | 1990-07-31 | — | — | US | disclosed |
| EP-0276065-B1 | ANTI-INFLAMMATORY AGENTS | ELI LILLY AND COMPANY (US) | 1990-06-06 | — | — | EP | disclosed |
| EP-0276065-A1 | Anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1988-07-27 | — | — | EP | disclosed |