Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 2/20 | 0.45 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARD | Q03181 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934988 | 0.95 | LTB4R (0.42) | LTB4RPLA2G2DTHRATHRBPPARG | |
| SCHEMBL10522356 | 0.89 | LTB4R (0.56) | LTB4RPLA2G2DTHRATHRB | |
| SCHEMBL6136991 | 0.88 | LTB4R (0.44) | LTB4RPLA2G2DTHRATHRBPPARG | |
| SCHEMBL6935194 | 0.88 | LTB4R (0.46) | LTB4RPLA2G2DTHRATHRBPPARG | |
| SCHEMBL8777238 | 0.88 | LTB4R (0.44) | LTB4RPLA2G2DTHRATHRBPPARG | |
| SCHEMBL9387348 | 0.87 | LTB4R (0.48) | LTB4RPLA2G2DTHRATHRB | |
| Hydrochloric Acid SCHEMBL9417918 | 0.86 | LTB4R (0.45) | LTB4RPLA2G2DTHRATHRBPPARG | |
| SCHEMBL9821862 | 0.86 | PLA2G2D (0.43) | LTB4RPLA2G2DTHRATHRBPPARG | |
| SCHEMBL9417841 | 0.85 | THRA (0.52) | LTB4RTHRATHRBPPARGPPARD | |
| SCHEMBL5711634 | 0.84 | LTB4R (0.53) | LTB4RPLA2G2DTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4202155-A | — | — | None | — | — | JP | disclosed |
| JP-4202155-A | — | — | None | — | — | JP | disclosed |
| US-8026282-B2 | Phenoxyalkylcarboxylic acid derivatives in the treatment of irritable bowel syndrome | MEDICINOVA, INC. (US) | 2011-09-27 | — | — | US | disclosed |
| US-20100285074-A1 | PHENOXYALKYLCARBOXYLIC ACID DERIVATIVES IN THE TREATMENT OF IRRITABLE BOWEL SYNDROME | MEDICINOVA, INC. | 2010-11-11 | — | — | US | disclosed |
| US-7786169-B2 | Phenoxyalkycarboxylic acid derivatives in the treatment of ulcerative colitis | MEDICINOVA, INC. (US) | 2010-08-31 | — | — | US | disclosed |
| EP-1744740-A4 | PHENOXYALKYCARBOXYLIC ACID DERIVATIVES IN THE TREATMENT OF INFLAMMATORY DISEASES | MEDICINOVA INC (US) | 2009-06-17 | — | — | EP | disclosed |
| US-20090093545-A1 | PHENOXYALKYCARBOXYLIC ACID DERIVATIVES IN THE TREATMENT OF IRRITABLE BOWEL SYNDROME OR ULCERATIVE COLITIS | MEDICINOVA, INC. | 2009-04-09 | — | — | US | disclosed |
| US-7429617-B2 | Phenoxyalkycarboxylic acid derivatives in the treatment of interstitial cystitis | MEDICINOVA, INC. (US) | 2008-09-30 | — | — | US | disclosed |
| EP-1744740-A1 | PHENOXYALKYCARBOXYLIC ACID DERIVATIVES IN THE TREATMENT OF INFLAMMATORY DISEASES | Medicinova, Inc. (US) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005105073-A1 | PHENOXYALKYCARBOXYLIC ACID DERIVATIVES IN THE TREATMENT OF INFLAMMATORY DISEASES | MEDICINOVA, INC. (US) | 2005-11-10 | — | — | WO | disclosed |
| US-4908368-A | SRS-A antagonist | MURASE KIYOSHI (JP) | 1990-03-13 | — | — | US | disclosed |
| US-4889871-A | ANTIINFLAMMATORY AGENTS; SELECTIVE LEUKOTRIENE ANTAGONISTS | G. D. SEARLE & CO. (US) | 1989-12-26 | — | — | US | disclosed |
| US-4855310-A | Thiadiazole compounds as antagonists of SRS-A | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-08-08 | — | — | US | disclosed |
| EP-0292977-A1 | Alkoxy-substituted dihydrobenzopyran-2-carboxylate derivatives | G.D. Searle & Co. (US) | 1988-11-30 | — | — | EP | disclosed |
| US-4740514-A | Tetrazole substituted compounds and their anti-allergic use | LILLY INDUSTRIES LIMITED (GB) | 1988-04-26 | — | — | US | disclosed |
| US-4714774-A | ANTIASTHMATIC OR ANTIINFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-12-22 | — | — | US | disclosed |
| EP-0186440-A2 | Method for producing benzoic acid derivatives | Takeda Chemical Industries, Ltd. (JP) | 1986-07-02 | — | — | EP | disclosed |
| US-4595540-A | Benzonitrile and benzothiocyano intermediates | LILLY INDUSTRIES LIMITED (GB) | 1986-06-17 | — | — | US | disclosed |
| EP-0181779-A1 | Heterocyclic compounds, their production, and medicaments containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1986-05-21 | — | — | EP | disclosed |
| EP-0180416-A2 | Benzoic acid analogues and their production | Takeda Chemical Industries, Ltd. (JP) | 1986-05-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100285074-A1 | PHENOXYALKYLCARBOXYLIC ACID DERIVATIVES IN THE TREATMENT OF IRRITABLE BOWEL SYNDROME | SI, SLC10A2, HCAR2 | LTB4R 262/4885PLA2G2D 2495/4885THRA 3035/4885 |
| US-20090093545-A1 | PHENOXYALKYCARBOXYLIC ACID DERIVATIVES IN THE TREATMENT OF IRRITABLE BOWEL SYNDROME OR ULCERATIVE COLITIS | SI, HCAR2, SUCNR1 | LTB4R 515/4885PLA2G2D 2974/4885THRA 2794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.