Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10288013 | 0.87 | MEN1 (0.40) | CYP3A4LMNAMAPTSMN1; SMN2ITGB3 | |
| SCHEMBL14641571 | 0.85 | CYP3A4 (0.51) | CYP3A4TSHRLMNAL3MBTL1MAPT | |
| SCHEMBL9417892 | 0.81 | CYP3A4 (0.41) | CYP3A4TSHRLMNAL3MBTL1MAPT | |
| SCHEMBL19219791 | 0.77 | ALDH1A1 (0.38) | CYP3A4L3MBTL1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL19945144 | 0.74 | ALDH1A1 (0.35) | CYP3A4L3MBTL1SMN1; SMN2GAAHTT | |
| SCHEMBL21017307 | 0.73 | TSHR (0.69) | CYP3A4TSHRLMNAL3MBTL1MAPT | |
| SCHEMBL13241065 | 0.72 | TDP1 (0.38) | CYP3A4TSHRLMNAL3MBTL1MAPT | |
| SCHEMBL9417807 | 0.72 | LTB4R (0.56) | CYP3A4TSHRNR1H4ALDH1A1HPGD | |
| SCHEMBL9417774 | 0.71 | HTT (0.40) | CYP3A4TSHRNR1H4HTTALDH1A1 | |
| SCHEMBL10973608 | 0.71 | ALDH1A1 (0.62) | CYP3A4TSHRLMNAMAPTCA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006315-A2 | METHODS OF IMMUNE MODULATION | POLYMEDIX, INC. (US) | 2012-01-12 | — | — | WO | disclosed |
| EP-2380872-A1 | Polycationic compounds and uses thereof | Polymedix, Inc. (US) | 2011-10-26 | — | — | EP | disclosed |