Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | CDC25B | P30305 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10031634 | 0.86 | MAPT (0.73) | ALDH1A1LMNAKDM4EMAPTHPGD | |
| SCHEMBL31336022 | 0.85 | HMGCR (0.54) | ALDH1A1LMNAKDM4EMAPTHPGD | |
| SCHEMBL9417833 | 0.84 | ALDH1A1 (0.64) | ALDH1A1LMNAKDM4EMAPTHPGD | |
| SCHEMBL28771416 | 0.80 | MAPT (0.68) | ALDH1A1LMNAKDM4EMAPTHPGD | |
| SCHEMBL9417940 | 0.79 | LTB4R (0.51) | ALDH1A1KDM4EKMT2AMEN1L3MBTL1 | |
| SCHEMBL2229650 | 0.78 | HPGD (0.59) | ALDH1A1LMNAKDM4EMAPTHPGD | |
| SCHEMBL29459452 | 0.78 | MAPT (0.75) | ALDH1A1LMNAKDM4EMAPTHPGD | |
| SCHEMBL225487 | 0.78 | MAPT (0.75) | ALDH1A1LMNAKDM4EMAPTHPGD | |
| SCHEMBL29372462 | 0.78 | MAPT (0.75) | ALDH1A1LMNAKDM4EMAPTHPGD | |
| SCHEMBL20177624 | 0.77 | CDC25B (0.51) | ALDH1A1LMNAKDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294613-A | Benzene derivatives of p-substituted ether and acid or ester | ELI LILLY AND COMPANY (US) | 1994-03-15 | — | — | US | disclosed |
| US-5098613-A | Aromatic ethers for treatment of mammals | ELI LILLY AND COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-4945099-A | LEUKOTRIENE ANTAGONIST | ELI LILLY AND COMPANY (US) | 1990-07-31 | — | — | US | disclosed |
| EP-0276065-B1 | ANTI-INFLAMMATORY AGENTS | ELI LILLY AND COMPANY (US) | 1990-06-06 | — | — | EP | disclosed |
| EP-0276065-A1 | Anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1988-07-27 | — | — | EP | disclosed |