Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | SHBG | P04278 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417898 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KMT2ASMN1; SMN2MEN1L3MBTL1 | |
| SCHEMBL9417837 | 0.83 | LMNA (0.55) | ALDH1A1KMT2ASMN1; SMN2MEN1SHBG | |
| SCHEMBL30096449 | 0.83 | KDM4E (0.51) | ALDH1A1KMT2ASMN1; SMN2MEN1L3MBTL1 | |
| SCHEMBL22939100 | 0.83 | ALDH1A1 (0.71) | ALDH1A1KMT2ASMN1; SMN2MEN1L3MBTL1 | |
| SCHEMBL22939099 | 0.83 | ALDH1A1 (0.71) | ALDH1A1KMT2ASMN1; SMN2MEN1L3MBTL1 | |
| SCHEMBL31335625 | 0.82 | MAPT (0.53) | ALDH1A1KMT2ASMN1; SMN2MEN1SHBG | |
| SCHEMBL12553675 | 0.82 | MAPT (0.53) | ALDH1A1KMT2ASMN1; SMN2MEN1SHBG | |
| SCHEMBL14056584 | 0.81 | ALDH1A1 (0.52) | ALDH1A1KMT2ASMN1; SMN2MEN1L3MBTL1 | |
| SCHEMBL4012873 | 0.81 | ALDH1A1 (0.52) | ALDH1A1KMT2ASMN1; SMN2MEN1L3MBTL1 | |
| SCHEMBL18944073 | 0.79 | KMT2A (0.63) | ALDH1A1KMT2ASMN1; SMN2MEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294613-A | Benzene derivatives of p-substituted ether and acid or ester | ELI LILLY AND COMPANY (US) | 1994-03-15 | — | — | US | disclosed |
| US-5098613-A | Aromatic ethers for treatment of mammals | ELI LILLY AND COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-4945099-A | LEUKOTRIENE ANTAGONIST | ELI LILLY AND COMPANY (US) | 1990-07-31 | — | — | US | disclosed |
| EP-0276065-B1 | ANTI-INFLAMMATORY AGENTS | ELI LILLY AND COMPANY (US) | 1990-06-06 | — | — | EP | disclosed |
| EP-0276065-A1 | Anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1988-07-27 | — | — | EP | disclosed |