SCHEMBL9418043

SCHEMBL9418043

O=C(O)C(F)(COc1ccccc1)Oc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.46
HDAC1 Q13547 2/20 0.45
HDAC2 Q92769 2/20 0.45
PPARG P37231 3/20 0.43
CYP2C19 P33261 2/20 0.42
CYP1A2 P05177 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
S1PR2 O95136 1/20 0.41
S1PR4 O95977 1/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
XBP1 P17861 1/20 0.41
HTT P42858 1/20 0.41
PAX8 Q06710 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
S1PR3 Q99500 1/20 0.41
S1PR5 Q9H228 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29564565 0.80 PPARG (0.41) ALOX15HDAC1HDAC2PPARGCYP2C19
SCHEMBL36735 0.78 ALOX15 (0.48) ALOX15HDAC1HDAC2PPARGCYP2C19
SCHEMBL27693074 0.78 ALOX15 (0.48) ALOX15PPARGCYP2C19MEN1KMT2A
SCHEMBL7507755 0.77 PPARG (0.39) ALOX15HDAC1HDAC2PPARGCYP2C19
SCHEMBL10887797 0.75 ALOX15 (0.42) ALOX15PPARGCYP2C19MEN1KMT2A
SCHEMBL23824908 0.72 ALDH1A1 (0.46) ALOX15HDAC1HDAC2CYP2C19LMNA
SCHEMBL17674534 0.72 SSTR4 (0.43) ALOX15HDAC1HDAC2PPARGCYP2C19
SCHEMBL9404914 0.72 HDAC1 (0.43) ALOX15HDAC1HDAC2PPARGMEN1
SCHEMBL4654238 0.72 PPARG (0.46) HDAC1HDAC2PPARGLMNAGAA
SCHEMBL2280790 0.72 ALDH1A1 (0.50) ALOX15HDAC1HDAC2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1279856-A None JP disclosed
JP-6305915-A None JP disclosed
JP-H06305915-A HERBICIDE COMPOSITION DOWELANCO 1994-11-01 JP disclosed
JP-H01279856-A FLUOROPHENOXYPHENOLS DOW CHEM CO:THE 1989-11-10 JP disclosed
US-4808750-A (PRE-OR POST-)EMERGENCE HERBICIDE FOR BROAD LEAF PLANTS THE DOW CHEMICAL COMPANY (US) 1989-02-28 US disclosed
US-4808750-A (PRE-OR POST-)EMERGENCE HERBICIDE FOR BROAD LEAF PLANTS THE DOW CHEMICAL COMPANY (US) 1989-02-28 US disclosed
US-4808750-A (PRE-OR POST-)EMERGENCE HERBICIDE FOR BROAD LEAF PLANTS THE DOW CHEMICAL COMPANY (US) 1989-02-28 US disclosed
US-4751329-A HERBICIDE INTERMEDIATES THE DOW CHEMICAL COMPANY (US) 1988-06-14 US disclosed
US-4751329-A HERBICIDE INTERMEDIATES THE DOW CHEMICAL COMPANY (US) 1988-06-14 US disclosed
US-4751329-A HERBICIDE INTERMEDIATES THE DOW CHEMICAL COMPANY (US) 1988-06-14 US disclosed
US-4684394-A Herbicidal aryloxyphenoxyalkanoate and alkenoate derivatives, compositions, and method of use therefor THE DOW CHEMICAL COMPANY (US) 1987-08-04 US disclosed
US-4642338-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1987-02-10 US disclosed
US-4642338-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1987-02-10 US disclosed
US-4642338-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1987-02-10 US disclosed
US-4550192-A PRE-AND POSTEMERGENCE HERBICIDES THE DOW CHEMICAL COMPANY (US) 1985-10-29 US disclosed
US-4550192-A PRE-AND POSTEMERGENCE HERBICIDES THE DOW CHEMICAL COMPANY (US) 1985-10-29 US disclosed
US-4550192-A PRE-AND POSTEMERGENCE HERBICIDES THE DOW CHEMICAL COMPANY (US) 1985-10-29 US disclosed
EP-0138359-A2 Herbicidal Fluorophenoxyphenoxypropionates, derivatives thereof and related compounds THE DOW CHEMICAL COMPANY (US) 1985-04-24 EP disclosed
EP-0138359-A2 Herbicidal Fluorophenoxyphenoxypropionates, derivatives thereof and related compounds THE DOW CHEMICAL COMPANY (US) 1985-04-24 EP disclosed
EP-0138359-A2 Herbicidal Fluorophenoxyphenoxypropionates, derivatives thereof and related compounds THE DOW CHEMICAL COMPANY (US) 1985-04-24 EP disclosed