SCHEMBL2280790

SCHEMBL2280790

FC(F)(F)COc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
LMNA P02545 3/20 0.50
MAPT P10636 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
KCNA3 P22001 1/20 0.50
S1PR2 O95136 1/20 0.50
S1PR4 O95977 1/20 0.50
GAA P10253 1/20 0.50
XBP1 P17861 1/20 0.50
HTT P42858 1/20 0.50
PAX8 Q06710 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
S1PR3 Q99500 1/20 0.50
S1PR5 Q9H228 1/20 0.50
GPR3 P46089 1/20 0.49
PIK3CD O00329 1/20 0.47
PIK3CA P42336 1/20 0.47
PIK3CB P42338 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28126443 0.98 LMNA (0.49) ALDH1A1LMNAMAPTMEN1KMT2A
Water SCHEMBL27843768 0.98 LMNA (0.49) ALDH1A1LMNAMAPTMEN1KMT2A
Formaldehyde SCHEMBL28103446 0.93 MAPT (0.50) ALDH1A1LMNAMAPTMEN1KMT2A
Phenol SCHEMBL28313835 0.89 LMNA (0.47) ALDH1A1LMNAMAPTMEN1KMT2A
Anisole SCHEMBL27928792 0.89 CA4 (0.56) ALDH1A1LMNAMAPTMEN1KMT2A
Acetonitrile SCHEMBL27860688 0.88 MAPT (0.46) ALDH1A1LMNAMAPTMEN1KMT2A
SCHEMBL2494091 0.88 MAPT (0.46) ALDH1A1LMNAMAPTMEN1KMT2A
SCHEMBL498377 0.87 ALDH1A1 (0.56) ALDH1A1LMNAMAPTMEN1KMT2A
SCHEMBL7467325 0.87 PIK3CD (0.54) ALDH1A1LMNAMAPTMEN1KMT2A
Acetaldehyde SCHEMBL27974244 0.86 MEN1 (0.45) ALDH1A1LMNAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250197345-A1 SYNTHESIS OF DIGLYCOLAMIDES UNITED STATES DEPARTMENT OF ENERGY 2025-06-19 US claimed
EP-4370733-A2 METHODS AND DEVICES FOR ENRICHING A SUBSTRATE WITH AN ALKALI METAL, AND ELECTROLYTE RENA Technologies GmbH (DE) 2024-05-22 EP claimed
CN-116864809-A Lithium ion battery electrolyte and application thereof 远景动力技术(江苏)有限公司 2023-10-10 CN claimed
WO-2023284918-A2 METHODS AND DEVICES FOR ENRICHING A SUBSTRATE WITH AN ALKALI METAL, AND ELECTROLYTE RENA Technologies GmbH (DE) 2023-01-19 WO claimed
CN-111816935-A Method of charging secondary lithium metal batteries to reactivate dead lithium with redox shuttle additives and battery control system incorporating the method 麻省固能控股有限公司 2020-10-23 CN claimed
US-7763602-B2 Pyrrole derivatives as antimycobacterial compounds LUPIN LIMITED (IN) 2010-07-27 US claimed
US-7691837-B2 Pyrrole derivatives as antimycobacterial compounds LUPIN LIMITED (IN) 2010-04-06 US claimed
EP-2079674-A1 PROCESS FOR THE PREPARATION OF TRIFLUOROETHOXYTOLUENES Grindeks, a joint stock company (LV) 2009-07-22 EP claimed
WO-2008055849-A1 PROCESS FOR THE PREPARATION OF TRIFLUOROETHOXYTOLUENES GRINDEKS, A JOINT STOCK COMPANY (LV) 2008-05-15 WO claimed
US-20040220409-A1 Flecainide synthesis MCDANIEL WILLIAM C 2004-11-04 US claimed
WO-2002066413-A1 FLECAINIDE SYNTHESIS NARCHEM CORPORATION (US) 2002-08-29 WO claimed
US-4643811-A PHOTOCHLORINATION RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1987-02-17 US claimed
US-12527779-B2 Prostaglandin E2 (PGE2) EP4 receptor antagonists DOMAIN THERAPEUTICS (FR) 2026-01-20 US disclosed
US-12357603-B2 Acyl sulfonamides for treating cancer BAYER AKTIENGESELLSCHAFT (DE) 2025-07-15 US disclosed
US-12336981-B2 Compounds and compositions for the inhibition of NAMPT VALO HEALTH, INC. (US) 2025-06-24 US disclosed
US-20250197345-A1 SYNTHESIS OF DIGLYCOLAMIDES UNITED STATES DEPARTMENT OF ENERGY 2025-06-19 US disclosed
EP-0023422-B1 HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THEM E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-02-22 EP disclosed
EP-0064322-A2 Benzenesulfonyl isocyanates, isothiocyanates, chlorides, and sulfonamides having a fluorinated substituent E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-11-10 EP disclosed
EP-0057546-A2 Sulfonylurea N-oxides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-08-11 EP disclosed
EP-0023422-A2 Herbicidal sulfonamides, preparation and use thereof, and compositions containing them E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-02-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527779-B2 Prostaglandin E2 (PGE2) EP4 receptor antagonists PTGER1, PTGER4, PTGER3 ALDH1A1 687/4885LMNA 1849/4885MAPT 4848/4885
US-20040220409-A1 Flecainide synthesis KCNH1, CYP3A43, CYP2F1 ALDH1A1 450/4885LMNA 2760/4885MAPT 4170/4885
US-12336981-B2 Compounds and compositions for the inhibition of NAMPT NAMPT, NNMT, NNT ALDH1A1 984/4885LMNA 860/4885MAPT 256/4885
US-12357603-B2 Acyl sulfonamides for treating cancer KAT6A, KAT6B, KAT2A ALDH1A1 1645/4885LMNA 3460/4885MAPT 4715/4885
US-20250197345-A1 SYNTHESIS OF DIGLYCOLAMIDES RPN2, FUT6, RPN1 ALDH1A1 2645/4885LMNA 1820/4885MAPT 4642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.