Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 4/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10593635 | 0.73 | CDK4 (0.43) | CDK4CCND1ESR1ESR2ALDH1A1 | |
| SCHEMBL5367335 | 0.72 | ESR1 (0.35) | ESR1ESR2ALDH2HSD17B10 | |
| SCHEMBL5353460 | 0.72 | ESR1 (0.35) | ESR1ESR2ALDH2HSD17B10 | |
| SCHEMBL9418189 | 0.71 | TRPV1 (0.50) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL5358039 | 0.70 | ESR1 (0.39) | ESR1ESR2ALDH2 | |
| SCHEMBL5350016 | 0.69 | ESR1 (0.34) | ESR1ESR2ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL21359025 | 0.67 | ALDH1A1 (0.49) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL9862532 | 0.66 | ESR1 (0.42) | ESR1ESR2ALDH2SMN1; SMN2NPC1 | |
| SCHEMBL9862642 | 0.66 | CNR2 (0.51) | HDAC3HDAC1HDAC2HDAC8TRPV1 | |
| SCHEMBL9862540 | 0.65 | ESR1 (0.39) | ESR1ESR2ALDH1A1GPR84HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346014-B1 | Therapeutic product for the treatment of peri- or postmenopausal conditions | ZENECA LTD (GB) | 1994-08-03 | — | — | EP | disclosed |