Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.51 |
| ▸ | CNR1 | P21554 | 8/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9418189 | 0.85 | TRPV1 (0.50) | TRPV1MAPTHDAC3HDAC1HDAC2 | |
| SCHEMBL9862582 | 0.84 | MTNR1A (0.47) | CNR2CNR1TRPV1 | |
| SCHEMBL5335468 | 0.82 | MTNR1A (0.52) | CNR2CNR1TRPV1HSD17B10MEN1 | |
| SCHEMBL9862542 | 0.80 | MTNR1A (0.44) | CNR2CNR1 | |
| SCHEMBL9862532 | 0.80 | ESR1 (0.42) | CNR1MAPT | |
| SCHEMBL9862446 | 0.79 | HDAC1 (0.59) | CNR2CNR1TRPV1HSD17B10MEN1 | |
| SCHEMBL5335473 | 0.78 | MTNR1A (0.52) | CNR2CNR1TRPV1HSD17B10MEN1 | |
| SCHEMBL7194125 | 0.75 | ESR1 (0.63) | TRPV1HSD17B10MEN1MAPTKMT2A | |
| SCHEMBL7193335 | 0.75 | ESR1 (0.63) | TRPV1HSD17B10MEN1MAPTKMT2A | |
| SCHEMBL7193607 | 0.75 | ESR1 (0.63) | TRPV1HSD17B10MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021414-A | Antiestrogen | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-06-04 | — | — | US | disclosed |
| US-4904661-A | ANTIESTROGENS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-27 | — | — | US | disclosed |
| US-4732912-A | ANTIESTROGENS, ANTITUMOR AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-03-22 | — | — | US | disclosed |
| EP-0124369-B1 | PHENOL DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-06-24 | — | — | EP | disclosed |
| EP-0124369-A1 | Phenol derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-07 | — | — | EP | disclosed |