Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.50 |
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862642 | 0.85 | CNR2 (0.51) | TRPV1MAPTHDAC1HDAC2HDAC8 | |
| SCHEMBL7379616 | 0.76 | TRPV1 (0.76) | TRPV1HPGDLMNATSHRHDAC1 | |
| SCHEMBL8744900 | 0.73 | HPGD (0.81) | TRPV1HPGDLMNATSHRHDAC1 | |
| SCHEMBL10593635 | 0.73 | CDK4 (0.43) | HPGDMAPTKDM4E | |
| SCHEMBL9862542 | 0.72 | MTNR1A (0.44) | HPGD | |
| SCHEMBL5335468 | 0.71 | MTNR1A (0.52) | TRPV1MAPTLMNA | |
| SCHEMBL9418191 | 0.71 | HDAC3 (0.33) | TRPV1HPGDHDAC1HDAC2HDAC8 | |
| SCHEMBL17589255 | 0.71 | HPGD (0.72) | TRPV1HPGDLMNATSHRHDAC1 | |
| SCHEMBL5263499 | 0.70 | TRPV1 (0.57) | TRPV1HPGDLMNAHDAC1HDAC2 | |
| SCHEMBL6136136 | 0.70 | TRPV1 (0.50) | TRPV1TOP2ATOP2BMAPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346014-B1 | Therapeutic product for the treatment of peri- or postmenopausal conditions | ZENECA LTD (GB) | 1994-08-03 | — | — | EP | disclosed |