SCHEMBL9418211

SCHEMBL9418211

C=C/C=C/[Si](/C=C/C=C)(c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
ALDH1A1 P00352 1/20 0.35
ALOX15 P16050 1/20 0.31
TGM2 P21980 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9418213 1.00 TSHR (0.35) TSHRALDH1A1ALOX15TGM2
SCHEMBL28631076 0.74 MAPT (0.32)
SCHEMBL28421127 0.74 ALDH1A1 (0.30) TSHRALDH1A1
SCHEMBL160241 0.74 ALDH1A1 (0.41) TSHRALDH1A1ALOX15TGM2
SCHEMBL28638586 0.70 MAPT (0.35) TSHR
SCHEMBL22772415 0.69 ALDH1A1 (0.35) TSHRALDH1A1TGM2
SCHEMBL11659900 0.67 ALDH1A1 (0.31) TSHRALDH1A1
SCHEMBL11659904 0.67 ALDH1A1 (0.31) TSHRALDH1A1
SCHEMBL11024215 0.67 ALDH1A1 (0.36) TSHRALDH1A1ALOX15TGM2
Biphenyl SCHEMBL5599687 0.66 ALDH1A1 (0.56) TSHRALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6321960-A None JP disclosed
JP-H06321960-A NEW ORGANOSILICON COMPOUND AND ITS PRODUCTION DENKI KAGAKU KOGYO KK 1994-11-22 JP disclosed