Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10335750 | 0.90 | P2RX7 (0.37) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL19196278 | 0.84 | GABRA1 (0.39) | GABRA1GABRB2FEN1 | |
| SCHEMBL23079390 | 0.84 | GABRA1 (0.44) | GABRA1GABRB2ESR1ESR2PRKCI | |
| SCHEMBL4517211 | 0.84 | GABRA1 (0.56) | MCL1GABRA1GABRB2 | |
| SCHEMBL7761403 | 0.82 | PRKCI (0.47) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL9419304 | 0.79 | TYR (0.58) | MEN1MAPTMAPK1HTTKMT2A | |
| SCHEMBL1461903 | 0.78 | KDM4E (0.39) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL9419270 | 0.77 | TYR (0.58) | KDM4EMEN1ALDH1A1MAPTHTT | |
| SCHEMBL2139522 | 0.76 | AKR1B1 (0.52) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL1512796 | 0.76 | PIM1 (0.41) | KDM4EMEN1ALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103333697-B | Nematic negative liquid crystal containing 2,3,5,6-tetrafluorotolane, synthetic method and application | FUJIAN SHAOWU YONGJING CHEMICAL CO LTD | 2015-06-03 | — | — | CN | claimed |
| CN-103333697-A | Nematic negative liquid crystal containing 2,3,5,6-tetrafluorotolane, synthetic method and application | Shanghai tianwen chemical co ltd | 2013-10-02 | — | — | CN | claimed |
| US-5087764-A | Deprotonation of a 1-substituted-2,3-difluorobenzene using an organometallic compound and reacting the reaction product with an electrophile | Merck Patent Gesellschaft mit beschrankter Hafung (DE) | 1992-02-11 | — | — | US | claimed |
| EP-4026860-A1 | BIO-ELECTRODE COMPOSITION, BIO-ELECTRODE, AND METHOD FOR MANUFACTURING BIO-ELECTRODE | Shin-Etsu Chemical Co., Ltd. (JP) | 2022-07-13 | — | — | EP | disclosed |
| EP-4015598-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS | Merck Patent GmbH (DE) | 2022-06-22 | — | — | EP | disclosed |
| US-10221114-B2 | Liquid crystal compound having tetrafluoro cyclohexadiene structure showing negative anisotropy, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2019-03-05 | — | — | US | disclosed |
| US-20160200980-A1 | LIQUID CRYSTAL COMPOUND HAVING TETRAFLUORO CYCLOHEXADIENE STRUCTURE SHOWING NEGATIVE ANISOTROPY, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2016-07-14 | — | — | US | disclosed |
| US-20160200980-A1 | LIQUID CRYSTAL COMPOUND HAVING TETRAFLUORO CYCLOHEXADIENE STRUCTURE SHOWING NEGATIVE ANISOTROPY, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2016-07-14 | — | — | US | disclosed |
| CN-103333697-B | Nematic negative liquid crystal containing 2,3,5,6-tetrafluorotolane, synthetic method and application | FUJIAN SHAOWU YONGJING CHEMICAL CO LTD | 2015-06-03 | — | — | CN | disclosed |
| CN-103333697-A | Nematic negative liquid crystal containing 2,3,5,6-tetrafluorotolane, synthetic method and application | Shanghai tianwen chemical co ltd | 2013-10-02 | — | — | CN | disclosed |
| EP-0363458-B1 | 2,3-DIFLUOROBENZENES | MERCK PATENT GMBH (DE) | 1994-08-03 | — | — | EP | disclosed |
| US-5087764-A | Deprotonation of a 1-substituted-2,3-difluorobenzene using an organometallic compound and reacting the reaction product with an electrophile | Merck Patent Gesellschaft mit beschrankter Hafung (DE) | 1992-02-11 | — | — | US | disclosed |
| EP-0400068-A1 | DERIVATIVES OF 2,3-DIFLUOROPHENOL | MERCK PATENT GmbH (DE) | 1990-12-05 | — | — | EP | disclosed |
| WO-1989008632-A1 | DERIVATIVES OF 2,3-DIFLUOROPHENOL | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160200980-A1 | LIQUID CRYSTAL COMPOUND HAVING TETRAFLUORO CYCLOHEXADIENE STRUCTURE SHOWING NEGATIVE ANISOTROPY, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | OCIAD2, CNOT1, OCIAD1 | KDM4E 4306/4885MEN1 2404/4885ALDH1A1 1621/4885 |
| US-10221114-B2 | Liquid crystal compound having tetrafluoro cyclohexadiene structure showing negative anisotropy, liquid crystal composition, and liquid crystal display device | OCIAD2, CNOT1, OCIAD1 | KDM4E 4306/4885MEN1 2404/4885ALDH1A1 1621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.